DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3 and Ascl1

DIOPT Version :9

Sequence 1:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_071779.1	Gene:	Ascl1 / 64186	RGDID:	71010	Length:	233	Species:	Rattus norvegicus

Alignment Length:	169	Identity:	47/169 - (27%)
Similarity:	75/169 - (44%)	Gaps:	42/169 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 QRSQVTPLVPQRPSTNG---------RANGSSSSSKKTRRRV------ASMAQRRAA-----NIR 94
            |..|::|:...:||..|         |...||....:.:||:      .|:.|::.|     |.|
  Rat    59 QAPQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNER 123

  Fly    95 ERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELLSGTPSNSHKSRSDVYGS 159
            ||.|:..:|..|..||..||..|..|::|::||||.|:.||..:.:||            |.:.:
  Rat   124 ERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLL------------DEHDA 176

  Fly   160 MNGHHQAP--PPAIHPHHLH--------PAAAYQRDFAS 188
            ::...||.  .|.|.|::.:        |.::|..|..|
  Rat   177 VSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGS 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	HLH	87..135	CDD:278439	21/52 (40%)
Ascl1	NP_071779.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..95		9/35 (26%)
		HLH	131..173	CDD:197674	18/53 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810