Protein Alignment Fer3 and NEUROG2

DIOPT Version :10

• Sequence 1: NP_524322.1
• Gene: Fer3 / 41411
• FlyBaseID: FBgn0037937
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_076924.1
• Gene: NEUROG2 / 63973
• HGNCID: 13805
• Length: 272
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 55/299 - (18%)
• Similarity: 100/299 - (33%)
• Gaps: 113/299 - (37%)

  Fly     8 WKMVNSTSP------------NAAATVGNIAYCY---------VLP----CICAIGIVGNIT--- 44
            |::...|||            ..|:.||:::..:         :||    ...||..:.:::
Human   132 WRLFAETSPRQESRLQLTRINQVASLVGSVSILFCGLISHNMEILPNFQATSVAIAFLASLSFYS 196

  Fly    45 ----------------NLMVLASRRLRAVS--------------YMYLRA-------LAVADLLC 72
                            |::..:.:.|...|              |::|..       |.:.....
Human   197 GMFNVRQFEFKRNPEENVLSESEQELARTSVILLMRQILSQRNFYLFLIMNFFQVFHLTIFSNFM 261

  Fly    73 MLFVLVFVSTEYLAKNGSSINQYKLYQIYQCHLML-------------TLINWAL-GAGVYVVVA 123
            |:||...:.||.|:.:..||.....:...||.::|             .||::.| ||...|::.
Human   262 MIFVDNLIPTEALSSSVRSIMYGAGFICPQCLVLLGQSWLKKYGYYKVILISFYLEGAAALVMLL 326

  Fly   124 LSLERYISIVFPMHFRTWNSPQRATRAIVIAFLIPAIFYVPYA------ITRYKGKQRFDLLQNV 182
            |..|.|..:...:           |..:||......:|.:|.|      :.::..:..|.|:  |
Human   327 LGQEHYYCLAVYL-----------TVIMVIVHTSLCLFNLPVADMVEADLPKFNRQPPFSLM--V 378

  Fly   183 TIYSMDDHPIYTTFYWQIYKWTREAILRFLPIIILTVLN 221
            .:.|.              .:||.| ....|::||:.||
Human   379 AVISA--------------LFTRPA-QSLAPMLILSKLN 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	bHLH_TS_FERD3L_NATO3	79..142	CDD:381421	17/76 (22%)
NEUROG2	NP_076924.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..69
		bHLH_TS_NGN2_ATOH4	104..172	CDD:381560	7/39 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..264		7/66 (11%)