Protein Alignment Fer3 and NEUROD2

DIOPT Version :10

• Sequence 1: NP_524322.1
• Gene: Fer3 / 41411
• FlyBaseID: FBgn0037937
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_006151.3
• Gene: NEUROD2 / 4761
• HGNCID: 7763
• Length: 382
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 62/241 - (25%)
• Similarity: 90/241 - (37%)
• Gaps: 84/241 - (34%)

  Fly     9 QPTYMPDVPFQPLWGQ-----------EAPPPP----------------IVPYQELIAGFPCTDL 46
            :|..:.|||....||.           :|||||                .||    :.|...|:.
Human     8 EPGLLSDVPKFASWGDGEDDEPRSDKGDAPPPPPPAPGPGAPGPARAAKPVP----LRGEEGTEA 68

  Fly    47 SLWQRSQVTPL-----------------VPQRPSTNGRANGSSSSSKKTRRRV-ASMAQRRAANI 93
            :|.:..:...|                 ..:||...|     ....|.|:.|: .|..:|:.||.
Human    69 TLAEVKEEGELGGEEEEEEEEEEGLDEAEGERPKKRG-----PKKRKMTKARLERSKLRRQKANA 128

  Fly    94 RERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELL-SG------------- 144
            |||.||.:||.|.|.||:.||.::..::||:|||||||..||..::|:| ||
Human   129 RERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLC 193

  Fly   145 ----------------TPSNSHKSRSDVYGSMNGHHQAPPPAIHPH 174
                            ..|.:..:.....|:...|....|.|:||:
Human   194 KGLSQPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPFAMHPY 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	bHLH_TS_FERD3L_NATO3	79..142	CDD:381421	30/63 (48%)
NEUROD2	NP_006151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		27/129 (21%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	36/96 (38%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		1/5 (20%)
		Neuro_bHLH	180..310	CDD:463621	8/60 (13%)