DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fer3 and NEUROD1

DIOPT Version :9

Sequence 1:NP_524322.1 Gene:Fer3 / 41411 FlyBaseID:FBgn0037937 Length:195 Species:Drosophila melanogaster
Sequence 2:NP_002491.3 Gene:NEUROD1 / 4760 HGNCID:7762 Length:356 Species:Homo sapiens


Alignment Length:193 Identity:54/193 - (27%)
Similarity:74/193 - (38%) Gaps:74/193 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 QRPSTNGRANGSSSSSKKTRRRVASMAQRR-AANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLS 123
            |:|...|     ....|.|:.|:.....|| .||.|||.||..||.|.|.||:.||.::..::||
Human    79 QKPKRRG-----PKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLS 138

  Fly   124 RIETLRLAITYIGFMAELL-SGTPSN--------------------------------------- 148
            :|||||||..||..::|:| ||...:                                       
Human   139 KIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPTTNLVAGCLQLNPRTFLPEQNQDM 203

  Fly   149 ----------------SHKS---RSDVYGSMNG---HHQAPPPAIHPHHLHPAAAYQRDFASP 189
                            |::|   .|..||:|:.   .|..|||     |.: :||.:..|.||
Human   204 PPHLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVFHVKPPP-----HAY-SAALEPFFESP 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fer3NP_524322.1 HLH 87..135 CDD:278439 26/48 (54%)
NEUROD1NP_002491.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..94 5/19 (26%)
bHLH_TS_NeuroD1 75..160 CDD:381562 36/85 (42%)
Nuclear localization signal. /evidence=ECO:0000255 87..93 1/5 (20%)
Neuro_bHLH 160..284 CDD:403655 17/107 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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