Protein Alignment Fer3 and ASCL2

DIOPT Version :10

• Sequence 1: NP_524322.1
• Gene: Fer3 / 41411
• FlyBaseID: FBgn0037937
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_005161.1
• Gene: ASCL2 / 430
• HGNCID: 739
• Length: 193
• Species: Homo sapiens
• Alignment Length: 180
• Identity: 51/180 - (28%)
• Similarity: 75/180 - (41%)
• Gaps: 51/180 - (28%)

  Fly    24 QEAPPPPIVPYQELIAGFPCTDLSLWQRSQVTPLVPQ--------RPSTNGRANGSSSSSKKTRR 80
            :.|||.|.||       ..|.       ::..|..|:        ||:|.....|:
Human     8 RSAPPAPPVP-------VGCA-------ARRRPASPELLRCSRRRRPATAETGGGA--------- 49

  Fly    81 RVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELLSGT 145
              |::|:|   |.|||.|:..:|..|..||:.||.....|:||::||||.|:.||..:..||:
Human    50 --AAVARR---NERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLA-- 107

  Fly   146 PSNSHKS-RSDVYGSMNGHHQAP-----PPAIHPHHLHPAAAYQRDFASP 189
               .|.: |:.:.|.:......|     ||...|    .||:..|..:||
Human   108 ---EHDAVRNALAGGLRPQAVRPSAPRGPPGTTP----VAASPSRASSSP 150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	bHLH_TS_FERD3L_NATO3	79..142	CDD:381421	24/62 (39%)
ASCL2	NP_005161.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		7/32 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..56		7/32 (22%)
		bHLH_TS_ASCL2_Mash2	49..112	CDD:381586	27/81 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..177		10/37 (27%)