DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3 and Neurod4

DIOPT Version :9

Sequence 1:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001099412.2	Gene:	Neurod4 / 288821	RGDID:	1310434	Length:	330	Species:	Rattus norvegicus

Alignment Length:	166	Identity:	50/166 - (30%)
Similarity:	67/166 - (40%)	Gaps:	53/166 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 RPSTNGRANGSSSSSKKTRRRVASMAQRRA-ANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSR 124
            :|...|     ....|.|:.|:.....||. ||.|||.||..||:|.|.|||.:|.::..::||:
  Rat    66 KPKRRG-----PKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSK 125

  Fly   125 IETLRLAITYIGFMAEL-------------------LSGTPSN----------------SHKSRS 154
            |||||||..||..::|:                   ||...||                ..:.:|
  Rat   126 IETLRLARNYIWALSEVLETGQTLEGKGFVEMLCKGLSQPTSNLVAGCLQLGPQSALLEKREEKS 190

  Fly   155 DVYGSMNGHH----QAP----PP----AIHPHHLHP 178
            .:..|....|    |:|    ||    ..||.||.|
  Rat   191 PICDSTVSVHSFNYQSPGLPSPPYGHMETHPLHLKP 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	HLH	87..135	CDD:278439	26/48 (54%)
Neurod4	NP_001099412.2	bHLH_TS_NeuroD4_ATOH3	59..145	CDD:381564	34/83 (41%)
Neurod4	NP_001099412.2	Neuro_bHLH	146..263	CDD:403655	16/81 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910