DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fer3 and PTF1A

DIOPT Version :9

Sequence 1:NP_524322.1 Gene:Fer3 / 41411 FlyBaseID:FBgn0037937 Length:195 Species:Drosophila melanogaster
Sequence 2:NP_835455.1 Gene:PTF1A / 256297 HGNCID:23734 Length:328 Species:Homo sapiens


Alignment Length:204 Identity:64/204 - (31%)
Similarity:95/204 - (46%) Gaps:58/204 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 PFQPLWGQEAPPPPIVPYQELIAGFPCTDLSLWQRSQVTPLVPQRPSTNGRA-NGSSSSSKKTRR 80
            |:.|     ..||..:.|       ||...::..           |....|. :|:::::.:.||
Human   112 PYSP-----GSPPSCLAY-------PCAGAAVLS-----------PGARLRGLSGAAAAAARRRR 153

  Fly    81 RVASMAQ----RRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAEL 141
            ||.|.|:    |:|||:||||||.::|:||:.||..:||..||||||:::||||||.||.|::||
Human   154 RVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSEL 218

  Fly   142 LS-------------GTPSNSHKSRSDVYGSM-------NGHHQAPPPAIHPHHLHPAAAYQRDF 186
            :.             |.|....:...|..||.       :...::|.|:...:.|.|.|      
Human   219 VQADLPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLA------ 277

  Fly   187 ASPYNHSLS 195
                .||||
Human   278 ----GHSLS 282

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fer3NP_524322.1 HLH 87..135 CDD:278439 29/51 (57%)
PTF1ANP_835455.1 HLH 165..220 CDD:238036 34/54 (63%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 259..278 5/28 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 305..328
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2562
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.840

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