DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3 and Ascl5

DIOPT Version :9

Sequence 1:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001257538.1	Gene:	Ascl5 / 226439	MGIID:	2685043	Length:	188	Species:	Mus musculus

Alignment Length:	205	Identity:	57/205 - (27%)
Similarity:	77/205 - (37%)	Gaps:	67/205 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 QHPHPIDQPTYMPDVPFQPLWGQEAPP-----PPIVPYQELIAGFPCTDLSLWQRSQVTPLVPQR 61
            |.|....:|  :.:|||....|...||     ..:.||......|...|.         |..|
Mouse    28 QTPLAATEP--LSNVPFLLYPGHSEPPYYDAYTGVFPYVPFPGAFGVYDY---------PFEP-- 79

  Fly    62 PSTNGRANGSSSSSKKTRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIE 126
                                  :..|:|  |.|||:|:..:||.:.:||..:|....|||||::|
Mouse    80 ----------------------AFIQKR--NERERQRVKCVNEGYARLRGHLPGALTEKRLSKVE 120

  Fly   127 TLRLAITYIGFMAELLSGTPSNSHKSRSDVYGSMNGHHQAPPPAIHPHHLH--------PAAAYQ 183
            |||.||.||.::.||||.||..                 |||||..|...|        |::...
Mouse   121 TLRAAIRYIKYLQELLSATPDG-----------------APPPATSPPPAHTGHSNVPQPSSLVA 168

  Fly   184 RDFASPYNHS 193
            ....||::.|
Mouse   169 ESSGSPFSSS 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	HLH	87..135	CDD:278439	23/47 (49%)
Ascl5	NP_001257538.1	HLH	86..136	CDD:197674	24/49 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810