DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3 and Lyl1

DIOPT Version :9

Sequence 1:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_032561.2	Gene:	Lyl1 / 17095	MGIID:	96891	Length:	278	Species:	Mus musculus

Alignment Length:	176	Identity:	50/176 - (28%)
Similarity:	71/176 - (40%)	Gaps:	54/176 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HPHPIDQPTYM-PDVPFQPLWGQEAPPPPIVPYQELIAGFPCTDLSLWQRSQVTPLVPQRPSTNG 66
            ||||.....|: |..||                            |::..|:    :.:|||.:.
Mouse   104 HPHPFLNSVYIGPAGPF----------------------------SIFPNSR----LKRRPSHSE 136

  Fly    67 RANGSSSSSKKTRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLA 131
            .........:|..|||.:       |.|||.|..::|.||.:||:.:||...:::||:.|.||||
Mouse   137 LDLADGHQPQKVARRVFT-------NSRERWRQQHVNGAFAELRKLLPTHPPDRKLSKNEVLRLA 194

  Fly   132 ITYIGFMAELL-----------SGTPSNSHKSRSDVYGSMN---GH 163
            :.||||:..||           |...|....:|..|.||..   ||
Mouse   195 MKYIGFLVRLLRDQTAVLTSGPSAPGSRKPPARRGVEGSARFGAGH 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	HLH	87..135	CDD:278439	19/47 (40%)
Lyl1	NP_032561.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46
		bHLH_TS_LYL1	145..209	CDD:381548	29/70 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..278		8/29 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810