DRSC/TRiP Functional Genomics Resources

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Protein Alignment MARS1 and GstE2

DIOPT Version :9

Sequence 1:NP_004981.2 Gene:MARS1 / 4141 HGNCID:6898 Length:900 Species:Homo sapiens
Sequence 2:NP_611324.1 Gene:GstE2 / 37107 FlyBaseID:FBgn0063498 Length:221 Species:Drosophila melanogaster


Alignment Length:144 Identity:34/144 - (23%)
Similarity:67/144 - (46%) Gaps:20/144 - (13%)


- Green bases have known domain annotations that are detailed below.


Human    48 VPVLQLDSGNYLFSTSAICRYFFLLSGWEQDD-----------LTNQWLEWEATELQPALS--AA 99
            ||:|: |:|..::.:.||..|  |:..:...|           ..:|.|.::|:.|..:|.  :.
  Fly    56 VPLLE-DNGALIWDSHAIVCY--LVDKYANSDELYPRDLVLRAQVDQRLFFDASILFMSLRNVSI 117

Human   100 LYYLVVQGKKGEDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPE 164
            .|:|.......::.:.:::.|..|:::.|.  :.|:|.|...::||:.. ||....|.....|.|
  Fly   118 PYFLRQVSLVPKEKVDNIKDAYGHLENFLG--DNPYLTGSQLTIADLCC-GATASSLAAVLDLDE 179

Human   165 -ELSALHSWFQTLS 177
             :...:.:||:.||
  Fly   180 LKYPKVAAWFERLS 193

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MARS1NP_004981.2 Thioredoxin_like <27..68 CDD:294274 7/19 (37%)
GstA <47..189 CDD:223698 34/144 (24%)
GST_C_MetRS_N 77..179 CDD:198340 25/115 (22%)
PRK12268 264..819 CDD:237029
MetRS_core 265..633 CDD:173907
'HIGH' region 273..283
'KMSKS' region 593..597
Anticodon_Ia_Met 642..771 CDD:153411
MetRS_RNA 845..889 CDD:238475
GstE2NP_611324.1 GstA 5..196 CDD:223698 34/144 (24%)
GST_N_Delta_Epsilon 5..78 CDD:239343 9/24 (38%)
GST_C_Delta_Epsilon 94..209 CDD:198287 24/103 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0625
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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