DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG18765

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_001097750.1	Gene:	CG18765 / 59149	FlyBaseID:	FBgn0042110	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	115/423 - (27%)
Similarity:	199/423 - (47%)	Gaps:	62/423 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PEWLNQTQFEELLAAHVDQFSKIVGFQVK-------PAMAPGENYATLMLRISIDVELTDKSTKL 119
            |.|:.:.:.|.|: ..:.:|.||...:.|       ||:.           :.|.|.:.|...:.
  Fly    17 PTWVEKKELEALV-KQISEFRKIESLRWKWETQLAEPALC-----------VHIQVLVADNKKRQ 69

  Fly   120 VCFMLKVPHNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDSVKEPK 184
            |.:::|.|..|| :...|.....|::|..::..:||.|||||:.....:.|.|      .|.:.|
  Fly    70 VSYLIKSPETVP-VGLKLPRTGDFSTERHMFEVVLPALEELYQNSDRIVHFGP------PVIQAK 127

  Fly   185 LANTVLMSD-LSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYEDQFVNGVMGG 248
            |.::.:..| :...|:...|.|:.|::...:..|.|||.:||.::           .::....|.
  Fly   128 LKSSHIYGDYILNKGYSVANGLKGLSVTAMEGVLSKLAAYHAGTA-----------AYIAKTPGK 181

  Fly   249 NKEVLMAFYEGMVASFRTALMANLKNFKNGEEFREKLEKAFVQIFLDFEHLMTADPD------EF 307
            .:| |....|...:...||.:.:|...:..|..|....:.:......|:..:.:..:      .|
  Fly   182 IRE-LPKLRENSKSDEETAELKSLYQLRFHESLRSNDARQYEDKVKSFQKYVKSGTEILDSKTSF 245

  Fly   308 NVLNHGDCWMNNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIR 372
            ||:.:|.||.||||.::|:.|.|:|.||..|...:||....|||..:||:.  ..|...|:.:::
  Fly   246 NVILNGSCWPNNLLLQVDAFGNVKDTLFSGFHTAQYGPAVYDLFSSLLTAP--AEKSSRFDGYVK 308

  Fly   373 HYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGDSE 437
            .||:||.::|:||.|.||:|||.:|.:.:.|:|.||...:..:|||||.|          .|:::
  Fly   309 FYHDQLIENLNLLKFLGKKPSLTDLQLDLLKYGHWAFETATEILPIVLSD----------FGNND 363

  Fly   438 SSAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLE 470
            ....|:|.::..:     |.:||||::|:|:.|
  Fly   364 IEELFRNPVFGEQ-----IRELLPWMENRGYFE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	77/298 (26%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG18765	NP_001097750.1	PKc_like	56..323	CDD:304357	77/287 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442568
Domainoid	1	1.000	53	1.000	Domainoid score	I7597
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850