DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CHKov1

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_001097918.1	Gene:	CHKov1 / 43067	FlyBaseID:	FBgn0045761	Length:	410	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	160/413 - (38%)
Similarity:	259/413 - (62%)	Gaps:	15/413 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PEWLNQTQFEELLAAHVDQFSKIVGFQVKPAMAPGENYATLMLRISIDVELTDKSTKLVCFMLKV 126
            |:|:...:||::|.::||.:||:..|:.:...|.|:||||.|||::|:|||.|.:||.:.:|:|:
  Fly     7 PDWVTAERFEDVLKSNVDGYSKVRNFKAEMGSAAGDNYATNMLRVNIEVELQDGTTKELSYMVKL 71

  Fly   127 PHNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDSVKEPKLANT--V 189
            |......::|:...|.|..|..:|:.::|::|.||||.|:::||..|:::|      |.|.|  :
  Fly    72 PRQREINKEMMKHNNIFEIERTMYNLVVPEMEALYKAAGVEVTFGAKSYEL------KNAQTEYI 130

  Fly   190 LMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYEDQFVNGVMGGNKEVLM 254
            .:.||...||||.||||.|:...|:..|:||||:|||:::.|...|.|.:..:||..   ||...
  Fly   131 SLEDLCIKGFKNANRLEGLDQAHTERVLRKLAQWHAATAVRVATKGQYPEIVLNGFF---KEENR 192

  Fly   255 AFYEGMVASFRTALMANLKNFKNGEEFREKLEKAFVQIFLD--FEHLMTADPDEFNVLNHGDCWM 317
            .....|:.......:.....::..|.:.||: ||...:.:|  |: :...||.|||||||||.|.
  Fly   193 PMMNDMMNGMGQVFVKCCSTYEGNEAYIEKV-KALKDVMIDELFK-MCVVDPTEFNVLNHGDSWS 255

  Fly   318 NNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIRHYHEQLTQHL 382
            ||::|:.|..|:::::..||||..|||:..|||:|.:::|..::.||..|:|:::.||:.|.:||
  Fly   256 NNIMFQYDESGKIKEVYMVDFQVSKYGTVAQDLYYFLISSTKLEDKLSKFDYYVKVYHDNLVEHL 320

  Fly   383 DLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGDSESSAKFKNLLY 447
            .:|.::...||||::|..:||:|::|...:.||:..||:||.|||:||||:|||...|.|:..:|
  Fly   321 KILKYSKPLPSLRDIHKSLYKYGTFAYSVATGVMAAVLVDPTESASFENFVGDSAEGADFQMKMY 385

  Fly   448 TNKRYHGYIEKLLPWLDNKGFLE 470
            .|.||..:::.:||||.|:|.|:
  Fly   386 NNPRYRKHMQAILPWLLNRGALD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	111/295 (38%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CHKov1	NP_001097918.1	EcKinase	41..325	CDD:397213	111/294 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442551
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850