DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG10550

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_651380.2	Gene:	CG10550 / 43061	FlyBaseID:	FBgn0039321	Length:	425	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	153/426 - (35%)
Similarity:	252/426 - (59%)	Gaps:	25/426 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 SSEQPENPKN--QILDWLNVSDFAEVISSAEPEFDKIVGGSWSSATKPGDNFASKLLKIDIETQL 546
            |:|:|.||..  .|..|:|...|..:|......||||:.....:||.||:|:.|.::::.::..|
  Fly     6 SAEKPVNPNEHLHIPKWINEEYFQPIIEKDVENFDKIINLVPIAATAPGENYTSIMIRVIVDILL 70

  Fly   547 KDHTSKTFSYILK--VQPKSTPDNFTDVNMFPKEMEMYQKYVPAFEQLYKDAGLTVTFTANSFVL 609
            ||.:.:..|||||  ::..|..|....:.:||||.:||:.::|.|.:|||:|||.:........:
  Fly    71 KDGSEQRVSYILKTMLEADSGADVIDGMGLFPKERKMYEVHIPQFVKLYKEAGLEIELAPKCLHV 135

  Fly   610 NKAVKEEYLLMENLQTKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKELNGAYPPLYNDGI 674
            :...:...::.|:|..:.||..||:||.::.|.:..|:|||:.||||:..||:||.|..:||..|
  Fly   136 DATDELITMVFEDLSRQNFKNFDRLKGFDLPHMREVLRKLAELHAASVVAKEINGPYDAMYNMSI 200

  Fly   675 YIEQTRDVFHNMFASAKEAYIRIFGTF--EGADEYLPKLEWIIDNHVD--QVLEDA----KINEQ 731
            |.||:||:|.::....:|.:::....:  |.|:.|:.:: |      |  :|.|:|    :::|.
  Fly   201 YNEQSRDLFESLGKQREEQFLKAMRNWDLENAESYIARM-W------DPLEVFEEAVQVNQVDED 258

  Fly   732 AFNVLNHGDAWINNIMFQYDAEGRLKETYLLDHQNAKYGNPAQDLYYFLISSAELDIKVDEFDNL 796
            .||||||||.|.|||||.|...|.:..|.|:|.|..|:|:|||||:|.:.:||.||||:.|||:.
  Fly   259 EFNVLNHGDCWSNNIMFNYKDNGEIDRTILVDLQVGKWGSPAQDLWYLITTSASLDIKIKEFDHF 323

  Fly   797 IRFYHENLVEHTKLLKYNGFVPSLSELHAILIEH----PAFAVGTVISTLTVCLTDEGFNPELFF 857
            |:.||:.|.|..|||.|:..:|:|.:||.:::::    |..|:|.:::||..  ||:..|.::..
  Fly   324 IQIYHQRLAECLKLLNYSKPIPTLRDLHIMMLKYGFWGPLTAMGVMVATLMP--TDKDANMKMIL 386

  Fly   858 VETPESEAFRTKLLGNERYKAHVEKIMPWLNRRGLL 893
            .:.||::|.|.:...|..|...::.::|:.:.:|||
  Fly   387 AQGPEADAIRYRTFINPYYAKAMKVLLPFFDNKGLL 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	114/293 (39%)
CG10550	NP_651380.2	EcKinase	53..340	CDD:281023	114/293 (39%)
CG10550	NP_651380.2	APH	108..338	CDD:279908	93/236 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442547
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850