DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6834 and CG13659

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_651378.1	Gene:	CG13659 / 43059	FlyBaseID:	FBgn0039319	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	101/434 - (23%)
Similarity:	195/434 - (44%)	Gaps:	36/434 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   478 VAPETPSSEQPENPKNQILDWLNVSDFAEVISSAEPEFD-KIVGGSWSSATKPGDNFASKLLKID 541
            :|.|:.:.::...|     :||||....:|:...|.:.: |::..|::.|:..||::||.:.:..
  Fly     1 MAEESFNDDELNPP-----EWLNVQFMTQVLRGYEKDSNLKVINLSFTPASAKGDHYASIMFRAR 60

  Fly   542 IETQLKDHTSK----TFSYILK---VQPKSTPDNFTDVNMFPKEMEMYQKYVPAFEQLYKDAGLT 599
            :|     :|::    |.|.|:|   |:.....|.|.|..:|..|:.||.|.:|.:|::.:.|...
  Fly    61 VE-----YTAQNGNFTKSLIIKTMIVEEGIKKDMFKDSPLFTTEIGMYTKVLPEWERILRRANDP 120

  Fly   600 VTFTANSFVLNKAVKEEYLLMENLQTKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKELNG 664
            ....... :.:.....:.|:.::|...|:.:. |.:.|..|...|:..|||:.||.|:|:.....
  Fly   121 AKLYVEC-IYHSLQPHQILIFDDLVEMGYAVV-RDRFLTREEISSAYSKLAKIHAISMKFIHEQP 183

  Fly   665 AYPPLYNDGIYIEQTRDVFHNMFASAKEAYIRIFGTFEGADEYLP---KLEWIIDNHVDQVLEDA 726
            .|...:.:|: .|....:..::.:...:.::.:.|......:|.|   |:.....:.:.:.:::.
  Fly   184 EYLKEFKNGL-CEMPGLIDSSIISGGMDPFMEMLGRIPELSKYQPHFKKISLHFKDRLRETMQEY 247

  Fly   727 KINEQ-AFNVLNHGDAWINNIMFQYDAE-GRLKETYLLDHQNAKYGNPAQDL---YYFLISSAEL 786
            :.|.| .:|||.|.|....|:||:.:.| |..::..|||:|.......|.||   .|.|:..|:
  Fly   248 RNNPQPGYNVLCHADFHSRNMMFKNNKETGCFEDCMLLDYQGCNVAPMAVDLMYSIYMLMGPAQ- 311

  Fly   787 DIKVDEFDNLIRFYHENLVEHTKLLKYNGFVPSLSELHAILIEHPAFAVGTVISTLTVCLTDEGF 851
              :.:|.|.|:.:|...|:|..|.:.|.|.:|:.....|.:..|..:....:.:.|.|.:   |.
  Fly   312 --RREELDILLNYYLSILLETLKKIGYQGSMPTEQGFWAEMKRHRYYEFLLLSTFLPVSI---GL 371

  Fly   852 NP-ELFFVETPESEAFRTKLLGNERYKAHVEKIMPWLNRRGLLD 894
            .. :|...:...:|..|.||...|.:....:.|:....:.|..|
  Fly   372 RTHKLDIGDMMHNEETRKKLYQLEDFMEETKSILDRFQKSGYFD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	72/298 (24%)
CG13659	NP_651378.1	EcKinase	48..336	CDD:281023	72/298 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459815
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840