DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG31097

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_733093.2	Gene:	CG31097 / 43058	FlyBaseID:	FBgn0051097	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	146/430 - (33%)
Similarity:	216/430 - (50%)	Gaps:	41/430 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   489 ENPKNQIL--DWLNVSDFAEVISSAEPEFDKIVGGSWSSATKPGDNFASKLLKIDIETQLKDHTS 551
            |||...::  .|||.|.|..:|:..||:|.||...:..:|..||.||||.:|::.::..:||.:.
  Fly     4 ENPNESLVVPKWLNKSKFESLIAKDEPDFTKIDQFTTVAAVPPGGNFASVMLRVYLDIVMKDGSQ 68

  Fly   552 KTFSYILKVQPKSTPDN--FTDVNMFPKEMEMYQKYVPAFEQLYKDAGLTVTFTANSFVLNKAVK 614
            |..||::|...:|....  ..::..|.||.:||..|:|.||::|:.||..|........:.:...
  Fly    69 KRKSYVVKTMLESDKGGKAVNEMRYFHKEQQMYSTYLPQFEKIYRVAGHPVQLMPKCLEIGEIDG 133

  Fly   615 EEYLLMENLQTKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKELNGAYPPLYNDGIYIEQT 679
            ..|.:.|:|.|:.|..|||.||:||||.:.||:|||:.||||:.|||   .|.|.:.|
  Fly   134 NIYFIFEDLSTRNFVAADRTKGVNMEHMRLSLRKLAELHAASVIYKE---RYGPYHAD------- 188

  Fly   680 RDVFHNMFASAKEAYIRIFGTFE-GADEYLPKLE-WIID-----------NHVDQVLEDAKINEQ 731
               |.|.|| .|:........|| .|.||...:: |.||           .:....||...::.|
  Fly   189 ---FDNGFA-RKDKIEHSVRRFEVKAPEYKAAMKTWGIDECYLKNFPTTEQYGKLCLESLNVDPQ 249

  Fly   732 AFNVLNHGDAWINNIMFQYDAEGRLKETYLLDHQNAKYGNPAQDLYYFLISSAELDIKVDEFDNL 796
            .||||.|||...:||:|:|:..|...|..:||.|..|:.:|.|||...:|.||..|....||||:
  Fly   250 DFNVLTHGDFSPSNILFKYNENGAPSEALILDFQICKWASPTQDLLMLIILSARKDSSYKEFDNI 314

  Fly   797 IRFYHENLVEHTKLLKYNGFVPSLSELH-AILIEHPAFAVGTVI------STLTVCLTDEGFNPE 854
            :|.|.|.|::..::|||...:|.|.||. ||..::..|:....:      ..|.||..:   |..
  Fly   315 VRIYWEYLIDFLRVLKYKKPLPQLRELQSAIYKKNNTFSAFFAVMNHLPGDLLPVCKEN---NLH 376

  Fly   855 LFFVETPESEAFRTKLLGNERYKAHVEKIMPWLNRRGLLD 894
            .|.:|....::||||:..|..:...|:::.|....|||.:
  Fly   377 TFNLEDEVGKSFRTKVYTNPIFVEVVKELYPICCNRGLFN 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	106/298 (36%)
CG31097	NP_733093.2	EcKinase	46..331	CDD:281023	106/298 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D27900at6960
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.940