DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG31098

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_733091.1	Gene:	CG31098 / 43057	FlyBaseID:	FBgn0051098	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	439	Identity:	112/439 - (25%)
Similarity:	198/439 - (45%)	Gaps:	53/439 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 KSNLGPEWLNQTQFEELLAAHV-DQFSKIVGFQVKPAMAPGE--NYATLMLRISIDVELTDKSTK 118
            |:...||||.....:::|..|. ::...:....||.|....:  .:|:.|.|.|.:::.......
  Fly     6 KNYQAPEWLTAEFLQDVLKEHFKEEQLAVTELIVKSAQVGDQAAGFASEMHRASFNLQRGTAPKG 70

  Fly   119 LVCFMLKVPHNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDSVKEP 183
            ....::| .|...|...:...:..|..|...|.::||:::.|.::.|.....||..:......||
  Fly    71 KFSVIVK-DHPKGQTGAVAHRSKLFKREILAYKEVLPRIQALLQSIGDQTKIAPTCYYTTESPEP 134

  Fly   184 KLANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYEDQFVNGVMGG 248
            .|    ::.|:...||:|..|...|||:.....::|:|:.||.|::..|               .
  Fly   135 FL----ILEDMQLSGFENFERGRLLNLDYVLPTIEKVAKLHACSALIAQ---------------D 180

  Fly   249 NKEVLMAFYEGMVA------SFRTALMANLK-------NFKNGEEFREKL----EKAFVQIFLDF 296
            :.|||..|.|..::      .|.|....|::       ::|..||..||:    |....:....|
  Fly   181 SPEVLEFFDEAPISRNPDRRDFLTFFPVNIRCVAEEVAHWKGYEEITEKMFNLAENVLQRALTMF 245

  Fly   297 EHLMTADPDEFNVLNHGDCWMNNLLFKLDSK-GEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHI 360
            |    :...:|.|.|..|.|:|||||.:::: .|..|::.:|||....||||.||.|.:..|::.
  Fly   246 E----STGKDFRVFNLTDLWINNLLFHINNETKEPDDVVTLDFQLAYVGSPTIDLNYFLYGSLNE 306

  Fly   361 DYKLDYFEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNE 425
            :.:..:::|.:|.|...|.|.|:.|.:.|..|:|:|:|:.:.|.....|..:..:.|::.   .|
  Fly   307 NVRKVHYKYIVREYQRVLQQTLEKLNYQGHIPTLKEIHIELIKTSLMGVIGATCLTPLIF---RE 368

  Fly   426 SATFENFLGD----SESSAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLE 470
            .|.||| |.|    :||..:|:.....|.:|..::::.:...:..|||:
  Fly   369 GAGFEN-LEDLNSRTESGDRFRRENVENPKYRAFLQRTIKEFELSGFLD 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	79/311 (25%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG31098	NP_733091.1	EcKinase	50..333	CDD:281023	79/306 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920