DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG31104

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_733090.1	Gene:	CG31104 / 43054	FlyBaseID:	FBgn0051104	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	436	Identity:	120/436 - (27%)
Similarity:	190/436 - (43%)	Gaps:	60/436 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PEWLNQTQFEELLAAHVDQFS--KIVGFQVKPAMAPGENYATLMLRISIDVELTDKSTKLVCFML 124
            |.||| .||...:....:|..  |:...||.||.|.|::||::|.|..  ||.|....|.  |..
  Fly    16 PAWLN-AQFIGDILREYEQLPDLKVTDLQVSPATAQGDHYASVMFRTK--VEYTTPKGKF--FKP 75

  Fly   125 KVPHNVPQME----QMLAMANFFNSENKVYSDILPKLEELYKAKGLDIT--FAPKAFKLDSVKEP 183
            .:...:|:.|    .||:.::.|.:|..:|...||:.|.:.:..| |.|  |.|..:  .|:| |
  Fly    76 LIIKTMPEQEGHKKDMLSESHLFETEIGMYCHALPEFERILREAG-DNTKLFVPCIY--HSLK-P 136

  Fly   184 KLANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYEDQFVNGVMGG 248
            :  ..::..||...|: .:.|....:|...|.|..|||::||. ||.|....||   |:
  Fly   137 R--QVMIFEDLVPQGY-TVIRDSPPSLGDLKLAFDKLAKWHAV-SMKVINEQPY---FL------ 188

  Fly   249 NKEVLMAFYE------------GMVASFRTAL--MANLKNFKNGEEFREKLEKAFVQIFLDFE-- 297
             ||.....:|            || .:|...|  |..|:.:|:  .| ||::..::| .|:.|
  Fly   189 -KEFQYGLFEMPTIDTDPFITTGM-TNFIEMLDKMPELRKYKH--HF-EKIKDNYMQ-RLEVEMH 247

  Fly   298 --HLMTADPDEFNVLNHGDCWMNNLLFKLDSK-GEVQDMLFVDFQNPKYGSPTQDLFYLILTSVH 359
              |....: |.:.||.|||..:.|::|:.:.: |...|::.||||.......|.||.|.:...:.
  Fly   248 EYHKYRRN-DRYYVLCHGDFHLRNMMFRHNKELGAYDDVMLVDFQLSNLCPITVDLTYSVYMLME 311

  Fly   360 IDYKLDYFEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPN 424
            .:.:.:..|..|..|...|...|..:|:.|..|:.|||...:..:..:..|.....|||::...:
  Fly   312 PEQRWEMGENLINEYFSVLVATLRKIGYKGDMPTQRELWEQIQNNKYYDFFLISTFLPIMVGVKS 376

  Fly   425 ESATFENFLGDSESSAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLE 470
            ........|.||:  |:.|:  |....|...:.|||...:..|:.:
  Fly   377 NDLKMHEALQDSQ--ARLKS--YFLDDYVQDVYKLLTKYEQLGYFK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	86/316 (27%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG31104	NP_733090.1	EcKinase	50..339	CDD:281023	86/316 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459811
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930