DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG11892

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_651372.1	Gene:	CG11892 / 43053	FlyBaseID:	FBgn0039313	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	122/435 - (28%)
Similarity:	202/435 - (46%)	Gaps:	28/435 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 PQLPCPIEKSNL--GPEWLNQTQFEELLAAHV-DQFSKIVGFQVKPAMAPGENYATLMLRISIDV 110
            |:...|.|.|..  .||||.::..::.|..:. ||..:|...:|.||:..||||..::.|:....
  Fly    19 PESLVPEETSVFLDAPEWLTESYLQDALRKYYKDQLIRINWVKVNPALGKGENYGGVLTRVKAQF 83

  Fly   111 ELTDKSTKLVCFMLKVPHNVPQMEQ-MLAMANFFNSENKVYSDILPKLEELYKAKG-LDITFA-P 172
            ..:|.|::|..:::|......:..| .:...:.||.|..:|..:|||.:.|.:..| .:..|| .
  Fly    84 TRSDGSSQLGHYIVKSTFEGNEFAQNAMKPYDIFNREMIIYEQVLPKQKALLREIGDAEQIFAET 148

  Fly   173 KAFKLDSVKEPKLANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASS-MNVQVN-- 234
            .|..:|:       :.::..||:..||...:||..|:.:..:..|:|||:.||.|: :|.:.|
  Fly   149 MAVDIDN-------SALIFEDLNARGFVMPDRLVGLDQKLARIVLRKLAKMHATSAVLNERENHI 206

  Fly   235 -GPYEDQFVNGVMGGNKEVLMAFYEGMVASFRTALMANLKNFKNGEEFREKLEKAFVQIFLDF-E 297
             ..|:..|.|.....        ||........|....:..:...|::.||| ||.|.|:::. :
  Fly   207 LESYDRGFFNRYTDN--------YEPAFVGMLQAATRRVAQWPGYEKYAEKL-KALVPIYMELGK 262

  Fly   298 HLMTADPDEFNVLNHGDCWMNNLLFKLDSK-GEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHID 361
            .:....|...|||.|||.|.||:|.|.|.: ||..|::.:|||...:|||..||||.:.:|:..|
  Fly   263 RIFDISPGHINVLAHGDLWTNNVLVKYDKQTGEPIDVVIIDFQYTAWGSPALDLFYFMNSSLEFD 327

  Fly   362 YKLDYFEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNES 426
            ...::.|..|.:|.......|..|.:....|||.:.|..:.:...:|...||.|.|:........
  Fly   328 LHQNHQEQLIAYYFRHFADTLKKLQYRSTIPSLHQFHQQLQQKKFYAAHTSISVFPVQRNVETAD 392

  Fly   427 ATFENFLGDSESSAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLEA 471
            |.|...:.:::.:..||:..|.|......:.:|||..:.:|.|:|
  Fly   393 ADFNALMENNQRAMNFKDACYRNPIAQRILRELLPDFEAEGLLDA 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	86/300 (29%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG11892	NP_651372.1	EcKinase	68..353	CDD:281023	86/300 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459419
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850