DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG10514

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_651371.1	Gene:	CG10514 / 43052	FlyBaseID:	FBgn0039312	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	126/428 - (29%)
Similarity:	209/428 - (48%)	Gaps:	34/428 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PEWLNQTQFEELLAAHV-DQFSKIVGFQVKPAMAPGENYATLMLRISIDVELTDKSTKLVCFMLK 125
            ||||.....|..|..|. |:...|...|:.||:.|||||..::.|..::..|::|...:...::|
  Fly     5 PEWLTHEYIEHALRCHYKDEGLTITQLQINPALGPGENYGGVLTRARVEFTLSNKEKNVQNLIVK 69

  Fly   126 VPHNVPQM-EQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDSVKEPKLANTV 189
            ...:..:: ::::|..:.:|.|..:|.::|||..||....|......|.|..:|   ..::|  :
  Fly    70 TEIDDDELTQELMAPYDIYNREMTIYQEVLPKCRELLNEIGDTERIFPTAIYVD---RERMA--I 129

  Fly   190 LMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASS-MNVQVNGPYE-------DQFVNGVM 246
            :..|||..|:...:|:..||.|.|...|:|||:||||:: :|.:.:|..|       :::.|...
  Fly   130 IFEDLSVVGYVMADRVRRLNEEHTHLILRKLAKFHAATAVLNERQSGCLESYDRGFFNRYTNAYS 194

  Fly   247 GGNKEVLMAFYEGMVASFRTALMANLKNFKNGEEFREKLEKAFVQIFLDF-EHLMTADPDEFNVL 310
            |       .|..|::|:.|  .|:.:....:   :.||| .|....::|. .......|.:.|||
  Fly   195 G-------YFVGGLLAAAR--WMSKVPTLAH---YGEKL-FALAPHYMDIGRECFAPTPGQVNVL 246

  Fly   311 NHGDCWMNNLLFKLD-SKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIRHY 374
            .|||.|.||::||.| :.|...|:|.:|||...:|||..||.:|..||:....:.|......:.|
  Fly   247 AHGDVWTNNVMFKYDPNTGRPVDVLLIDFQYSFWGSPCIDLHHLFNTSLKEPLRRDQQNGLFQFY 311

  Fly   375 HEQLTQHLDLLGFTGKQ-PSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGDSES 438
            |:..|:.|:.|.:...| |||.:..:.:.:...:|:..::.|.|:::......|.|...:.|.|.
  Fly   312 HKIFTETLEKLNYRQNQIPSLHQFKLEVEQKRFFALHSTVVVQPVMISQDPTDACFNALMNDDER 376

  Fly   439 SAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLEAYFINQ 476
            ..:|||.||.|......:..|:|:.|.||.||   :||
  Fly   377 GIRFKNRLYNNPTVQQNLHSLVPFFDRKGLLE---VNQ 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	88/302 (29%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG10514	NP_651371.1	EcKinase	39..324	CDD:281023	88/302 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459451
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850