DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG10513

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	120/429 - (27%)
Similarity:	194/429 - (45%)	Gaps:	45/429 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PEWLNQTQFEELLA-AHVDQFSKIVGFQVKPAMAPGENYATLMLRISIDVELTDKSTKLVCFMLK 125
            ||||::|..|.||. ...|...:|....:|||.|.|:|||::|.|:.|             ..||
  Fly    16 PEWLDETYLERLLRDLKNDPGLRITDLVIKPATAKGDNYASVMTRVRI-------------LFLK 67

  Fly   126 VPHNVPQMEQMLAMANFFN---------------SENKVYSDILPKLEELY-KAKGLDITFAPKA 174
            .....|:.|..:....:.|               :|.::|..|||:|..|. |.:..:..|| |.
  Fly    68 SGAKSPETEYYIVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEKTRQPEKVFA-KT 131

  Fly   175 FKLDSVKEPKLANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYED 239
            ..:|...|     .::..||:...:...:||...:||.|:..|:|||:.|||:::..:.......
  Fly   132 LHVDYEHE-----AIIFEDLAVTKYVLADRLVGFDLEHTRLGLRKLAKMHAAAAVLNERQPGLLT 191

  Fly   240 QFVNGVMGGNKEVLMAFY---EGMVASFRTALMANLKNFKNGEEFREKLEKAFVQIFLDFEHLMT 301
            :|.:|:...:.:....|:   .|:.|.|.....      :.||.:..||:|...::......:..
  Fly   192 KFDHGIFNRHTQAFAPFFVNTVGVAADFARECP------ELGERYATKLKKLQERVMEYSTRVYD 250

  Fly   302 ADPDEFNVLNHGDCWMNNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDY 366
            ..|.:||.|.|||.|:||::.:.....|..||..:|||...:.||..||.|...|||.:|.:.:.
  Fly   251 PQPGDFNTLVHGDYWVNNVMLRYGENKEPLDMTLIDFQFCSWSSPAVDLHYFFNTSVQVDIRYEQ 315

  Fly   367 FEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFEN 431
            .:...::||..|.:.|..|.|.|..|:||:..:.:.:...:||..::....|:..|.|..|.|..
  Fly   316 QDALFQYYHTVLVETLKDLNFGGYIPTLRQFVLQLERGRFFAVTVALVCQAILTNDQNADADFNA 380

  Fly   432 FLGDSESSAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLE 470
            .:.|.|....|:.:||||||....:::.||..|..|.|:
  Fly   381 LMKDDERGRNFRKVLYTNKRLQDNLKRELPRFDRSGLLD 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	80/310 (26%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	80/310 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850