DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG11889

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_001287526.1	Gene:	CG11889 / 3772506	FlyBaseID:	FBgn0039308	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	120/425 - (28%)
Similarity:	207/425 - (48%)	Gaps:	19/425 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 PIEKSNLGPEWLNQTQFEELLAAHV-DQFSKIVGFQVKPAMAPGENYATLMLRISIDVELTD-KS 116
            |.:.::..|.||.:...|:.|..:. :....:....:|||.|.|||||::|.|||::....| |.
  Fly     2 PEKTTHNAPAWLTEEYVEKKLRVYFKNDTLNLKKLTIKPATANGENYASVMTRISVEYITKDSKD 66

  Fly   117 TKLVCFMLKVPH-NVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDSV 180
            .:...|:||... :......:|.....:..|..:|..|||:|.::.|.:..|   :.|.|.. :|
  Fly    67 NQSATFLLKTTFADKDPAAHLLINYGIYTREIDMYEQILPRLADIVKNELHD---SRKLFAA-TV 127

  Fly   181 KEPKLANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVN-GPYEDQFVNG 244
            ...:..::::..|||.:.:|...|::.|:||.|...|:|||.||||.:...|.. |.:|..:..|
  Fly   128 GVDRERDSIMFEDLSLERYKVACRVKKLDLEHTYLVLEKLADFHAAGAALAQRQPGIFEKNYDRG 192

  Fly   245 VMGGNKEVLMAFYEGMVASFRTALMANL---KNFKNGEEFREKLEKAFVQIFLDF-EHLMTADPD 305
            ..  ||.|  ..||.::.:...||...|   .:.|  |.::.|::: .:...:|: |...:..|.
  Fly   193 FF--NKHV--RGYEPIMKNILKALSRTLDLSPDLK--ERYQAKIDR-LIDNVMDYGERSTSVAPG 250

  Fly   306 EFNVLNHGDCWMNNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYF 370
            :|..|.|||.|..|::|:.|.:|...:.:|:|||...:.||..||.|...||:|.:.:|:.....
  Fly   251 DFVTLAHGDIWTTNVMFQYDDEGHPVNAIFIDFQFSVWNSPAIDLQYFFSTSIHENLRLERQTEL 315

  Fly   371 IRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGD 435
            ::.|..:|...|:.:.::||.|||.|........|.:|||.|:...|.::.:..|..:.|.|:..
  Fly   316 VQFYFYKLVVALERVKYSGKVPSLFEFQQQFRTKGFYAVFASLIFEPTMVYNGKEEPSIEQFMTS 380

  Fly   436 SESSAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLE 470
            .|...:.::.:|..:.....:...||:||..|.|:
  Fly   381 DEKGVRLRDAVYQTEENLKKLHLTLPFLDQLGLLD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	87/298 (29%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG11889	NP_001287526.1	EcKinase	44..332	CDD:281023	87/298 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459371
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940