DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and F59B1.10

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_872223.1	Gene:	F59B1.10 / 353438	WormBaseID:	WBGene00019101	Length:	428	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	96/369 - (26%)
Similarity:	149/369 - (40%)	Gaps:	88/369 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 EQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDS--VKEPKL-ANTVLMSDLS 195
            |||.|   :|.|..|             |....::.|...|.|.:|  :..||: ..|.|....|
Worm   107 EQMYA---YFESSCK-------------KMHNQEMNFYEVAGKFNSKTLLIPKVYFYTKLDEKNS 155

  Fly   196 QDGFKNLNRLE----------CLNLEQTKFALKKLAQFHAASSMNVQVNGPYE-----DQFVNGV 245
            ..||..:..:|          | .:|:.:..|:.:|:..|.|..|     |.|     .:..||.
Worm   156 NKGFIGMEYVEGSIVRHSYDTC-TIEEIQPILRAIAKLQALSLQN-----PAEISKDLQKIDNGA 214

  Fly   246 MGGNKEVLMAFYEGMVASFRTALMANLKNFKNGEEFREKLEKAFVQIFLDFE---HLMTADPDEF 307
            :......:|....|:...|...  .||:..:.||:. :::|:...:| ||||   :|......:.
Worm   215 IFQETLKMMLSESGIKGIFEQC--RNLERSRFGEKV-DRIEEKRNEI-LDFEKAFNLNKVVGIKQ 275

  Fly   308 NVLNHGDCWMNNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSV-------HIDYKLD 365
            |||.|||.|..|.|: .::.|.......||:|....|:|.:||..|:::::       |....|:
Worm   276 NVLCHGDLWAANFLW-TENNGVFCATRIVDYQMSHLGNPAEDLVRLLVSTITGADRQAHWQQILE 339

  Fly   366 -YFEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIV-LLDPNESAT 428
             ::.||           |:.|| :|:.|...|...|.:|    ..|| :|.|.:: |..|...|.
Worm   340 QFYSYF-----------LNELG-SGEAPYTLEQLKLSFK----LYFP-VGALALLPLFGPAVDAK 387

  Fly   429 FENFLGDSESSAKFKNLLYTNKRYHGYIEKLLPWLDNKGFLEAY 472
            .|..  |||.:.|.:         |..|||:...||:   ||.|
Worm   388 LEGM--DSEKAEKCR---------HVVIEKVACLLDD---LEKY 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	69/281 (25%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
F59B1.10	NP_872223.1	DUF1679	8..422	CDD:369592	96/369 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810