DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG33511

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_001014492.2	Gene:	CG33511 / 3346223	FlyBaseID:	FBgn0053511	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	101/409 - (24%)
Similarity:	173/409 - (42%)	Gaps:	59/409 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LLAAHVDQFSK-IVGFQVKPAMAPGENYATLMLRISIDVELTDKSTKLVCFMLKVPH-NVPQMEQ 135
            |:.:.||..|| ::|:.       ||.|   .|.:..:|:...|...|..|:..:|. |.||.|:
  Fly    27 LINSQVDAGSKDLMGYM-------GEYY---KLHLEAEVKGDKKKYFLNYFIKSLPRKNEPQREE 81

  Fly   136 MLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLDSVKEPKLANTVLMSDLSQDGFK 200
             ......|..|:.:||.||||::: |..|.|    .||.:...:       :.:::.||:|| ::
  Fly    82 -CERKGVFQKESALYSQILPKIQK-YATKKL----YPKCYYSRN-------DILVLEDLTQD-YR 132

  Fly   201 NLNRLECLNLEQTKFALKKLAQFHAAS-----SMNVQVNGPYEDQFVNGVMGGNKEVLMAFYEGM 260
            :|...|...|:..|..|:.|::.||||     ..||::...|::..:...:..|....:...:.:
  Fly   133 HLRANEYYTLDHYKIVLEHLSELHAASIAWEEKENVKIYESYKNVLIELHLDSNNSWYITGLKAI 197

  Fly   261 VASFRTALMANLKNFKNGEEFREKLEKAFVQIFLDFEHLMTADPDEFNVLNHGDCWMNNLLFKLD 325
            |  |..|...:.:..|.....::||    ..:....|.|:.......|||.|.|.|.:|:::..:
  Fly   198 V--FLAARNPHFQTMKAQNFIQDKL----YNLLTKAEELVAPSKTIRNVLCHRDTWDHNIVYYFN 256

  Fly   326 SKGEV--QDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIRHYHEQLTQHLDLLGFT 388
            .:..|  .....||||..:|.|||.|:.:|:......:.:...::..:.||::.|..|||.||..
  Fly   257 KESSVLPNACCIVDFQLTQYCSPTLDVLFLLYIVASAEVRRAIYDECLEHYYKNLQHHLDRLGLD 321

  Fly   389 ---------GKQPSLRELHMLMYKHGSWAVF-PSIGVLPIV--LLDPNESATFENFLGDSESSAK 441
                     .|:.....|..|:.    ||:. |...:.|.:  .|...|...|:.:|....|..
  Fly   322 KNLITENNFRKECQRTRLAALVI----WALTEPQTKMSPSISNRLRSEEPEKFDYYLNCDRSEL- 381

  Fly   442 FKNLLYTNKRYHGYIEKLL 460
               ||...:...||.|.::
  Fly   382 ---LLRVIEIQPGYEETIM 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	77/299 (26%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG33511	NP_001014492.2	PKc_like	41..319	CDD:304357	77/307 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459712
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940