DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG31974

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_001259800.1	Gene:	CG31974 / 33174	FlyBaseID:	FBgn0051974	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	408	Identity:	97/408 - (23%)
Similarity:	172/408 - (42%)	Gaps:	67/408 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   489 ENPKNQILDWLNVSDFAEVISSAEPEFDKIVGGSWSSATKPGDNFASKLLKIDIETQLKDHTSKT 553
            |.||        :.:..:||....||...:...|.|..||||||:.|.:|.:..:.:..|...:.
  Fly     3 EVPK--------IKNLPQVIEPHLPEGCTLDSYSTSYLTKPGDNYGSIMLSVQAKIRSADGGIRD 59

  Fly   554 FSYILKVQPKSTPDNFTDVNMFPK-----EMEMYQKYVPAFEQLYKDAGLTVTFTANSF------ 607
            ...|.|: |..|.|.:..: ..|:     |..:||...|..::|..::|:......:.|
  Fly    60 LPLIAKL-PPLTNDLYWQI-FQPERTCITENAVYQYLSPELDKLQLESGILPAQIFDGFPRYYGS 122

  Fly   608 ---VLNKAVK---EEYLLMENLQTKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKELNGAY 666
               :.|:|.|   :..|:.||:.|:|::..:|.:..|:..|...|..|||:||..|..:
  Fly   123 RVSLDNRATKVDRDAVLVQENVTTRGYRPGNRHRPYNLAETVLILHYLAQYHALPIALR------ 181

  Fly   667 PPLYNDGIYIEQTRDVF--HNMFASAKEAYIRIFGTFEGADEYLPKLEWIID-----NHVDQVLE 724
              |....:|.|..|..|  .:|.::..:|...|..     .|.|..::.:..     |.|.::|:
  Fly   182 --LKKPQVYEEYVRPYFKKFDMNSNIDQAETEIMN-----KEILKDIKLVTSDERDVNRVKELLD 239

  Fly   725 -------DAKINEQAFNVLNHGDAWINNIMFQY---DAEGRLKETYLLDHQNAKYGNPAQDLYYF 779
                   ...:::..|..|.|||.||||:|.:|   ..||...:..::|.|.|:||:...|:.:.
  Fly   240 IFQAFQASNDVDDGPFTTLVHGDLWINNMMLKYGMRGEEGTPLKVKIVDFQIAQYGSLVHDIIFV 304

  Fly   780 LISSAELDIKVDEFDNLIRFYHENLVE-------HTKLLKYNGFVPSLSELHAILIEHPAFAVGT 837
            |.||.::::..|.|.|.:..|:...::       .|....|..|:..:.:...:.:.|..|.:..
  Fly   305 LFSSVDVNVLEDNFYNFLTIYYNAFIQTLRSVNVDTSNYTYELFLEEVQQTAHVQLPHAIFMMKV 369

  Fly   838 VI---STLTVCLTDEGFN 852
            ::   ||:.....|..|:
  Fly   370 ILADNSTIPKDYKDVDFS 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	78/324 (24%)
CG31974	NP_001259800.1	EcKinase	35..337	CDD:281023	77/316 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459632
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840