DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG7135

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_573269.1	Gene:	CG7135 / 32793	FlyBaseID:	FBgn0030895	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	99/411 - (24%)
Similarity:	182/411 - (44%)	Gaps:	18/411 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   498 WLNVSDFAEVISSAEPEFD-KIVGGSWSSATKPGDNFASKLLKIDIETQLKDHTSKTFSYILKVQ 561
            :|....|...:.....:.| :::|...::.|:.|:|:.|.:.:..|:.:..:..:...|.|:|..
  Fly    11 YLTPQFFRRTLEHGLQQLDLQVIGVQLTNLTRGGENYCSNIYRAQIKYRNAESCAMETSLIVKSM 75

  Fly   562 PKSTPDNFTDVNMFPKEMEMYQKYVPAFEQLYKDA--GLTVTFTANSFVLNKAVKEEYLLMENLQ 624
            |.........::::.||...|....|..|.|...|  ..:....|.....:....|:.:::|:|.
  Fly    76 PDEKQAILARLHIYNKETLFYMHIKPKLEALMWRAVDSFSAWTLAPKHYYSTTQPEQTIILEDLC 140

  Fly   625 TKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKE-----LNGAYP--PLYNDGIYIEQTRDV 682
            ..|:::..|..||:.:|....:.|||::||.::...|     :...||  .|:.|.|..|.
  Fly   141 AAGYQLKCRQLGLDFDHAALVMAKLAEYHALTMVMAEREPETIVDRYPFGLLHMDAINSEP---- 201

  Fly   683 FHNMFASAKEAYIRIFGTFEGADEYLPKLEWIIDNHVDQVLEDAKINEQAFNVLNHGDAWINNIM 747
            |..:|.:.......:.|..||......||....::..::||:.........|||||||.|:|||.
  Fly   202 FKLLFGTQLLKLAALVGDCEGFGGITTKLYRYHEHFTERVLKAVYPLRGNHNVLNHGDLWVNNIF 266

  Fly   748 FQYDAEGRLKETYLLDHQNAKYGNPAQDLYYFLISSAELDIKVDEFDNLIRFYHENLVEHTKLLK 812
            |:||||..:::..::|.|...||:...|:.|||.:|.||::..|....|:..|:.:||:..|.|.
  Fly   267 FKYDAEYTVQQVKIIDFQLCFYGSLGFDINYFLNTSLELEVLRDRRQELVDIYYRSLVDCLKHLP 331

  Fly   813 YNGFVPSLSELHAILIEHPAF----AVGTVISTLTVCLTDEGFNPELFFVETPESEAFRTKLLGN 873
            ::..:||..::...:.:..|:    |.|.......:.:..|..:.:.|..||...:..:....||
  Fly   332 WSKELPSYEDIMDEIRKREAYGFFVAFGFFPLMSMIGVDSEDNSLKNFHDETFARQKVQLMFEGN 396

  Fly   874 ERYKAHVEKIMPWLNRRGLLD 894
            .|....::..:..|:...|.|
  Fly   397 TRTLESLKCTLKRLDELKLFD 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	79/292 (27%)
CG7135	NP_573269.1	EcKinase	43..330	CDD:281023	78/290 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459253
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850