DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG31099

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_733099.1	Gene:	CG31099 / 326117	FlyBaseID:	FBgn0051099	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	134/418 - (32%)
Similarity:	221/418 - (52%)	Gaps:	35/418 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PEWLNQTQFEELLAAHVDQFSKIVGFQVKPAMAPGENY-----ATLMLRISIDVELTDKSTKLVC 121
            |:|::.....:.:.:.::.     |.|: .::.|..:.     .|::|.|.:.|:|.|.:.|.:.
  Fly     7 PDWVSSLSLNQAVHSVLED-----GVQI-TSVIPSVHLIQFRNCTVLLPIQVKVQLRDFTMKKLF 65

  Fly   122 FMLKVPHNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDITFAPKAFKLD-SVKEPKL 185
            |:||..|.......::.....|..|::||.::||||||:|:..|..::|.|:||:|| |:.
  Fly    66 FLLKAQHGTDIQAMVMNQLKMFQREHQVYHNVLPKLEEIYREVGKKVSFGPRAFRLDYSIG---- 126

  Fly   186 ANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQVNGPYEDQFVNGV-MGGN 249
            ...||:.||....:||:.|....|....|..|||||||||||::.|:.:|.:.:..|||| ...|
  Fly   127 VQYVLLEDLKAKSYKNVERQAGFNKLCLKQVLKKLAQFHAASAVCVEKHGAFSNLLVNGVYTKAN 191

  Fly   250 KEVLMAFYEGMVASFRTALMANLKNFKNGEEFREKL---EKAFVQIFLDFEHLMTADPDEFNVLN 311
            :.||....:..:      .::.|:.::.|:.|.::|   ||..|...|   .|.:.|.:||||||
  Fly   192 ESVLQELNDPEI------FLSQLRRWRLGDHFHKRLVEKEKDLVDGLL---KLHSPDSNEFNVLN 247

  Fly   312 HGDCWMNNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIRHYHE 376
            |.|||:||::||.|..|.|:|...:|:|..|||||..||:|.||:|...|.||..|:..:::|..
  Fly   248 HSDCWVNNVMFKFDDSGHVEDTALLDYQLVKYGSPAIDLYYTILSSAEKDIKLAQFDNMVQYYFY 312

  Fly   377 QLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGDSESSAK 441
            .|..:|..|.|.|..|.|:.:...:.|:|..|.......|||.:::..|....|.:      ::|
  Fly   313 HLLDNLKALNFGGSLPQLQHIRDALNKNGLAAYVVVTRALPITMMNQFEDEVNERY------ASK 371

  Fly   442 FKNLLYTNKRYHGYIEKLLPWLDNKGFL 469
            .|..::|:::|...|:.:|||::.:..|
  Fly   372 MKCAMFTSRKYIQAIKDILPWMEERSLL 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	109/301 (36%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG31099	NP_733099.1	EcKinase	44..323	CDD:281023	108/291 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850