DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG31436

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_733096.1	Gene:	CG31436 / 318734	FlyBaseID:	FBgn0051436	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	111/430 - (25%)
Similarity:	198/430 - (46%)	Gaps:	34/430 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   485 SEQPENPKNQILD-------WLNVSDFAEVISSAEPEFD-KIVGGSWSSATKPGDNFASKLLKID 541
            |..|:|  ||..|       |||....|.|:...|.|.. |::..::|.|:..||::||.:.:..
  Fly     2 SGNPQN--NQFNDDELVPPEWLNSEFMARVLEGNELEAAVKVIDLTFSPASAKGDHYASIMFRAR 64

  Fly   542 IE-TQLKDHTSKTFSYILKVQPKS---TPDNFTDVNMFPKEMEMYQKYVPAFEQLYKDAGLTVTF 602
            :: |..|....|  |.|:|..|::   ..|......:|..||.:|.|.:|.||::.:..|.....
  Fly    65 VKYTNRKGEFQK--SLIIKTMPEAEGHKKDMLGGSPIFETEMGLYTKVLPEFERILRQVGDDTQL 127

  Fly   603 TANSFVLNKAVKEEYLLMENLQTKGFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYKELNGAYP 667
            ..|. :.:.....:.|:.|:|...|: :..|.:...::..:....|||:|||.|:|.:.....:.
  Fly   128 YVNC-IYHSLEPHQVLIFEDLAEMGY-IVLRDRDATLDEIRRIYFKLAKWHAVSLKVQNEQPEFL 190

  Fly   668 PLYNDGIYIEQTRDVFHNMF-ASAKEAYIRIFGTFEGADEYLPKLEWIIDNHVDQVLEDAK---- 727
            ..|..|::  :...|.::.| .:..|.::.:.|.....::|.|..|.|.|:.:::::|:.|
  Fly   191 ESYTHGLF--EMPHVLNDPFMRTGMEFFVELLGKEPELNKYKPYFESIKDDFLERLVEEWKDIRK 253

  Fly   728 -INEQAFNVLNHGDAWINNIMFQYDAEGRLKETYLLDHQNAKYGNPAQDLYYFLISSAELDIKVD 791
             ..:..:.||.|||..:.||||::.....|::..|||.|.:.......||.|.:....|.:.:.:
  Fly   254 SQKKDEYWVLCHGDLHLRNIMFKHKDTVSLEDCMLLDFQISNLFPLTFDLLYSIYMLLEPEHRWN 318

  Fly   792 EFDNLIRFYHENLVEHTKLLKYNGFVPSLSELHAILIEH---PAFAVGTVISTLTVCLTDEGFNP 853
            .:|:||.:|...|.:..|.:.|.|.:||.|.|...|.:|   ..|.:.|.: .|...|.|:..:
  Fly   319 NWDDLINYYISVLQDVLKKIGYKGVMPSQSGLWKRLHQHKYYEFFLISTFL-PLMWALRDKSVD- 381

  Fly   854 ELFFVETPESEAFRTKLLGNERYKAHVEKIMPWLNRRGLL 893
               |.:..::|..|.|...::.|...|..::..|::.|||
  Fly   382 ---FGDLLQNEEKRRKCSFSKGYIKEVTILLARLDQLGLL 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	72/293 (25%)
CG31436	NP_733096.1	EcKinase	52..340	CDD:281023	72/293 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840