DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG2004

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_001259353.1	Gene:	CG2004 / 31809	FlyBaseID:	FBgn0030060	Length:	425	Species:	Drosophila melanogaster

Alignment Length:	405	Identity:	86/405 - (21%)
Similarity:	160/405 - (39%)	Gaps:	92/405 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   504 FAEVISS-AEPEFDKIV---GGS------WSSATKPGDNFASKLLKIDI-----------ETQLK 547
            ||::.:. :|...|:|:   ||:      :..:.|.||.:.|::.:|.|           |.||:
  Fly     7 FADISAKFSEATLDEIIRNAGGTRHTSYKFGPSGKKGDAYLSRVFRITIYGVKEAEEGQDEKQLE 71

  Fly   548 DHTSKTFSYILKVQPKSTPDN------FTDVNMFPKEMEMYQKYVPAFEQLYKDAGLTVTFTANS 606
                      :.|..|:.|||      |..|..|..|:..|.|.:||.|...|..
  Fly    72 ----------ISVIVKAMPDNLHRRRLFRSVIFFRNEINFYTKVLPAIEAFQKSR---------- 116

  Fly   607 FVLNKAVKE-----------------EYLLMENLQTKGFKMADRMKGLNMEHTKSSLKKLAQWHA 654
               ..|.|:                 :::.:|::..:|::...|...:::|....:::.|.::|.
  Fly   117 ---QPAPKKPFVEYPRCLASLCDGVNDFIALEDVGPRGYRAPVRQDYISLEDALLTMRTLGRFHG 178

  Fly   655 ASIKYKELN--------GAYPPLYNDGIYIEQTRDVFHNMFASAKEAYIRIFGTFEGADEYLP-- 709
            .::.:..|:        |:....|    |.|.||:.:......|:..      ..:...:..|
  Fly   179 VALAFNALDSKNFEKAAGSLEETY----YGEHTREWYTGFLLLAENV------ATDAVKQIYPNS 233

  Fly   710 KLEWIIDNHVDQVLEDAKIN----EQAFNVLNHGDAWINNIMFQYDAEGRLKETYLLDHQNAKYG 770
            |.|.:..|.:...|.|..||    ....:|..|||.|..|.:.:|:..|:.:|..::|.|.|:..
  Fly   234 KYETVATNFLQPPLFDDLINLVSTRSKLSVFGHGDCWTPNFLTKYNERGQSEEIIIIDFQLARCS 298

  Fly   771 NPAQDLYYFLISSAELDIKVDEFDNLIRFYHENLVEHTKLLKYNG-FVPSLSELHAILIEHPAFA 834
            :.|.||.:|:.|....:::...:|.|:|.|.|:..:..:.|..|. .:.|...|...|.....|.
  Fly   299 SLALDLSFFIYSCTSQELREQHYDELLRAYLESAQDLIQDLGGNAESIISWESLQEELKNFGRFG 363

  Fly   835 VGTVISTLTVCLTDE 849
            .|..|.:|.:.:.::
  Fly   364 CGMGIESLPMTMMED 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	70/331 (21%)
CG2004	NP_001259353.1	EcKinase	42..340	CDD:281023	69/330 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010