DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG32195

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_001262006.1	Gene:	CG32195 / 317907	FlyBaseID:	FBgn0052195	Length:	401	Species:	Drosophila melanogaster

Alignment Length:	405	Identity:	96/405 - (23%)
Similarity:	188/405 - (46%)	Gaps:	73/405 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   525 SATKPGDNFASKLLKID-IETQLKDHTSKTFSYILKVQPKSTPDNFTDVNMFP-------KEMEM 581
            :.::.|:||.|.:.::. :..:..|...::..||||             ::.|       .|.:|
  Fly    33 AVSQKGENFCSVIYRVALVFRRSPDGALESGKYILK-------------DLLPAAAALGTNEKDM 84

  Fly   582 YQKYVPAFEQLYKDAGLTV---TFTANSFVLNKAVKEEYLLMENLQTKGFKMADRMKGLNMEHTK 643
            ::..:||.:.:.::|...:   ..:|:..::..:..:|..::|:|...|::..||.:|||:|..|
  Fly    85 FEVLLPAMQAILEEAPKEIGEHKLSADCLLVEISAGKELYILEDLGALGYESFDRRQGLNLEEAK 149

  Fly   644 SSLKKLAQWHAAS-IKYKE----LNGAYPPLYNDGIYIEQTRDVFHNMFASAKEAYIRIFGTFEG 703
            ..::||||:|.|| :.|::    :....|..|.:|:         ::.||.|.        ..||
  Fly   150 ICVRKLAQFHGASKVLYEKKPELIQRLSPSHYANGL---------NDRFAQAL--------VLEG 197

  Fly   704 AD-------EYLPKLE-----WIIDNHVDQVLEDAKINEQAFNVLNHGDAWINNIMFQYDAEGRL 756
            |:       |.||::.     .|...:..::.:....|:.:.|.:.|||.|:|||||.:..
  Fly   198 AEYAAEAFAEELPEISKKMKAQIPKAYTKRMRDVVDPNKSSLNAVIHGDPWLNNIMFDFVN---- 258

  Fly   757 KETYLLDHQNAKYGNPAQDLYYFLISSAELDIKVDEFDNLIRFYHENLVEHTKLLKYNGFVPSLS 821
            |:..|:|.||..:|:||.|||:...:|.:.::.::..|.|:.:|.:||:|..:...|...:|:..
  Fly   259 KKATLVDFQNCYWGSPAIDLYFLFYTSLKPELLLNNQDELLNYYFDNLLETLRHCGYKDTLPTFG 323

  Fly   822 ELHAILIEHPAFAVGTVISTLTVCLTDEGFNPEL-------FFVETPESEAFRTKLLGNERYKAH 879
            :|...:.....:...||:..|.:|..    :||.       .||:|......|.:|..:||.:..
  Fly   324 QLKDEMKRCLFYGYYTVVCELPICCA----SPEASVDFGVHTFVDTDAMLKKRHQLFASERVRQT 384

  Fly   880 VEKIMPWLNRRGLLD 894
            ::..:...:|.|:|:
  Fly   385 IKATLLMFDREGILE 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	77/311 (25%)
CG32195	NP_001262006.1	EcKinase	37..315	CDD:281023	77/311 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459483
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850