DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and CG13360

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_569859.1	Gene:	CG13360 / 31025	FlyBaseID:	FBgn0025620	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	444	Identity:	122/444 - (27%)
Similarity:	197/444 - (44%)	Gaps:	57/444 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 EKSNLG---PEWLNQTQFEELLA-----AHVDQFSKIVGFQVKPAMAPGENYATLMLRI------ 106
            ::..||   |::||:..|:..|.     ..|| ..||: |. :.:...||||.:.:.|.
  Fly     6 KQKRLGHEPPKYLNEDFFKAALEDGLRDMRVD-IKKII-FS-ESSGGGGENYCSKIYRAKALYRS 67

  Fly   107 ---SIDVELTDKSTKLVCFMLKVPHNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGLDI 168
               .:|.||.     |:...:.:......:|::..    :..|...|.|:|.|||.|.   |...
  Fly    68 SKRQLDEELA-----LIVKSIAITPATQFLEELAV----YLREKIFYFDVLGKLEVLI---GDGS 120

  Fly   169 TFAPKAFKLDSVKEPKLANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAASSMNVQV 233
            .|..|.  |.:.:||  ..|::..||:|.|:|..:|...||.|.....||||.:|||:|.:..:.
  Fly   121 KFGAKC--LYTTREP--IQTIVFDDLTQYGYKLASRQSGLNEEHCVVILKKLGKFHASSMVLAEK 181

  Fly   234 NGPYEDQFVNGVMGGN----KEVLMAFYEGMVASFRTALMANLKNFKNGEE-FREKLEKAFVQIF 293
            .....:.|..|::..|    .|..:.|   |....||  :||:.:...|.| ..|||.:....|
  Fly   182 EPSVREHFTTGMLDENYIRTNERFINF---MTLQCRT--LANVVSKWPGYELLAEKLHRHCDNI- 240

  Fly   294 LDFEHLMTAD---PDEFNVLNHGDCWMNNLLFKLDSKGEVQ--DMLFVDFQNPKYGSPTQDLFYL 353
              .|:|:|..   |.|..||||||.|:||.::|.|.:...:  |.:||||||..:|||..|:.:.
  Fly   241 --KENLVTTGRPLPGEITVLNHGDLWVNNFMYKYDDEQPTKPIDAIFVDFQNSFFGSPGCDINFF 303

  Fly   354 ILTSVHIDYKLDYFEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGVLPI 418
            :.:||.:|..:...|:.|:.|:..|...|:.: .:...||..::...:.....:..|.|...||:
  Fly   304 LNSSVQLDVLIHRREFLIQTYYASLRDSLERM-HSAFVPSYADIQQEIRARELYGFFSSYAFLPM 367

  Fly   419 VLLDPNESATFE-NFLGDSESSAKFKNLLY-TNKRYHGYIEKLLPWLDNKGFLE 470
            |.:...:|.... ..|.|.:.:.|...|:: :|.|....:...|...|:.|..:
  Fly   368 VTMKKEDSYDISIEALSDQDFAKKKVQLMFSSNPRTTDTLRYALRRFDDLGIFD 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	93/310 (30%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
CG13360	NP_569859.1	EcKinase	50..335	CDD:281023	93/308 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850