DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and T16G1.3

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_506237.2	Gene:	T16G1.3 / 188553	WormBaseID:	WBGene00011797	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	89/382 - (23%)
Similarity:	161/382 - (42%)	Gaps:	83/382 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 FMLKVP---HNVPQMEQMLAMANFFNSENKVYSDILPKLEELYKAKGL----------------- 166
            |:||:.   |.:..::||       |.::|..|.:....|  |:|:||
Worm    44 FVLKITSCMHVLNVLDQM-------NLQDKSESALWSIFE--YEAQGLHNREVNLYEIIGKWNMD 99

  Fly   167 DITFAPKAF---KLDSVKEPK--LANTVLMSDLSQDGFKNLNRLECLNLEQTKFALKKLAQFHAA 226
            |:..:||.|   |.||....|  .|...:.:.:::..:.||...|..::      ||.||.|.|.
Worm   100 DVLMSPKVFFSKKFDSENLTKGFFAMEYVDNAITRHLYINLKSYELHSI------LKSLAVFQAE 158

  Fly   227 SSMNVQVNGPYEDQFVNG-----VMGGNKEVLMAFYEGMVASFRTALMANLKNFKNGEEFREKLE 286
            |   :::| ..|.:.|.|     ::|     .|....|:.:.|......      |.||..|..:
Worm   159 S---LKLN-KREQESVTGYDLEKIVG-----KMFSQNGLNSIFEQVRQI------NKEELSEAAD 208

  Fly   287 KAFVQIF----LDFEHLMTADPDEF-----NVLNHGDCWMNNLLFKLDSKGEVQDMLFVDFQNPK 342
            |  :.:|    ::|:  :..:.:.:     |||.|||.|..|:::| ::|.|.:....:|:|:..
Worm   209 K--IAVFGVELVNFD--LVKNLNNYLGIKKNVLVHGDLWSANIMWK-ENKDEFRVDKIIDYQSIH 268

  Fly   343 YGSPTQDLFYLILTSVHIDYKLDYFEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSW 407
            .|:|.:||..|.::::....:..|:|..:..::|...:.|:..........|:|.:.|.:..||.
Worm   269 LGNPAEDLVRLFISTLSGSERQKYWEKLLEQFYEYFIEALEDKNVPYTLEQLKESYRLYFVTGSL 333

  Fly   408 AVFPSIGVLPIVLL----DPNESATFENFLGDSESSAKFKNLLYTNKRYHGYIEKLL 460
            .:.|..|.:..|.|    ||:|...:...|     :.|.|.||...:..|.|..:::
Worm   334 LMLPMFGPIAEVKLAEMSDPDEVKKYREIL-----TEKTKRLLNDMEHRHLYTREII 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	70/303 (23%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
T16G1.3	NP_506237.2	PKc_like	1..381	CDD:389743	88/376 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820