DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6834 and F56A4.5

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_503669.1	Gene:	F56A4.5 / 186348	WormBaseID:	WBGene00018913	Length:	418	Species:	Caenorhabditis elegans

Alignment Length:	449	Identity:	102/449 - (22%)
Similarity:	156/449 - (34%)	Gaps:	146/449 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   500 NVSD---FAEVISSAEPEFDKIVGGSWSSATKPGDNFASKLLKIDIETQLKDHTSKTFSYILKVQ 561
            |:||   |...|:..||:        |..|.| ..|..|| ..:.|.|||   ....||.|.|
Worm    42 NISDLKGFQSKIALIEPD--------WVGAEK-NQNLPSK-FAVKISTQL---AFAVFSKITK-- 91

  Fly   562 PKSTPDNFTDVNMFPKEMEMYQKYVPAFEQLYKDAGLTVTFTANSFVLNKAVKEEYLLMENLQTK 626
                   |...|.|.:|...:                          |.|.::|.:    |.:.:
Worm    92 -------FDGGNGFGEEKLKF--------------------------LGKFIREGH----NREVE 119

  Fly   627 GFKMADRMKGLNMEHTKSSLKKLAQWHAASIKYK-ELNG---------AYP-PLY---------- 670
            .:|:.:::...::.|||:       ::....|.| :|.|         .:| |:|
Worm   120 AYKLLEKLNHPDIPHTKA-------YYLKPFKDKFDLKGFMILDFVPNVHPMPMYESIPADDLIS 177

  Fly   671 -----------NDGIYIEQT-----RDVFHNMFAS--AKEAYIRIFGTFE---GAD-----EYLP 709
                       .:.:..||.     .|:|..||..  ..|...|:.|..:   ||.     |...
Worm   178 LVRGVATFAGHGESLTAEQRSFARGSDIFELMFEEMYPDEQLERVCGVIQATFGAKNPAVVEECI 242

  Fly   710 KLEWIIDNHVDQVLEDAKINE-QAFN-VLNHGDAWINNIMFQYDAEGRLKETYLLDHQNAKYGNP 772
            ||.||..|.:...   :|::| ..|. ||||||.|.:|::...|..|.|....::|.|......|
Worm   243 KLFWIYKNSIKSY---SKVSELLGFKLVLNHGDLWQSNMLHCLDEHGNLVLKAIIDWQGVSMLPP 304

  Fly   773 AQDLYYFLISSAELDIKVDEFDNLIRFYHENLVEHTKLLKYNGFVP----SLSELH-AILIEHPA 832
            ..||...|:.......:.:....|:..||:.         :.|.|.    ||.||. :..:.:|
Worm   305 GLDLARLLMGCLTAYERRERGAELLMLYHQT---------FTGIVGEELFSLEELQDSYNLYYP- 359

  Fly   833 FAVGTVISTLT-VCLTDEGF-NPELFFVETPESEAFRTKLLG------NERYKAHVEKI 883
                  |.||| |.:....| |.|:..||..::   |.|..|      .:..|.|.:.:
Worm   360 ------IMTLTLVPMVSSLFENSEMSEVEKTQA---RLKTEGKLFALLEDLVKVHEQNV 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023	70/332 (21%)
F56A4.5	NP_503669.1	DUF1679	3..409	CDD:369592	102/447 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810