DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and F48G7.12

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_503277.2	Gene:	F48G7.12 / 186000	WormBaseID:	WBGene00018623	Length:	435	Species:	Caenorhabditis elegans

Alignment Length:	437	Identity:	97/437 - (22%)
Similarity:	181/437 - (41%)	Gaps:	83/437 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LLAAHV--DQFSKIVGFQVKPAMAPGEN-----------YATLMLRIS-----IDVELTDKSTKL 119
            |...||  :...|::|.|:......|||           :::.::.:.     .|..|.:|....
Worm    17 LFQTHVQLEDVQKVIGEQMNTKARLGENTKYTVIGDGNGFSSRVILVEPEWTVSDKHLPEKFVLK 81

  Fly   120 VCFMLKVPHNVPQM----------EQMLAMANFFNSENKVYS-DI-LPKLEELYKAKGLDITFAP 172
            :...|.||..:.||          ::....|.|.|...|::: :: |.|:.|.:...  :...:|
Worm    82 ITSCLHVPGLIEQMKGKNPGTFPAQEAALWAIFENEAQKLHNREVNLYKITEKWNKN--ETMLSP 144

  Fly   173 KAF---KLDSVKEPKLANTVLMSDLSQDGFKNLNRLECLNLEQTKF--ALKKLAQFHAASSMNVQ 232
            |.:   |.|:..:.|   .:|  .:..||...:..:.| |::..:.  .|:.:|...|.|....:
Worm   145 KIYFYKKFDAENKTK---GIL--GMEFDGNVTVRHIYC-NVKPRELYPVLRSIATLQAGSLHLTK 203

  Fly   233 -----VNGPYEDQFVNGVMGGNKEVLMAFYEGMVASFRTALMANLKNFKNGEEFREK--LEKAFV 290
                 ::|....|.:..:|  |.|.:..|||      :|..:       |.:...||  :.:||.
Worm   204 DEIESISGLDVKQMMGSLM--NNEGMKGFYE------QTREI-------NRKRLTEKTNVVEAFG 253

  Fly   291 QIFLDFEHLMTADPDEF-----NVLNHGDCWMNNLLFKLDSKGEVQDMLFVDFQNPKYGSPTQDL 350
            |..::||  :..:.:::     :|:.|||.|..|:|:|...:|.......:|:|....|:|.:||
Worm   254 QEVVNFE--LACNLNKYIGIKRDVMVHGDLWAANILWKEKDEGTFSVSKVIDYQLIHMGNPAEDL 316

  Fly   351 FYLILTSVHIDYKLDYFEYFIRHYHEQLTQHLDLLGFTGKQPSLRELHMLMYKHGSWAVFPSIGV 415
            ..|.|:::....:..::|..:..::   |..|..||......||.:|     |......|.|.|:
Worm   317 VRLFLSTLSGADRQAHWERLLEKFY---TYFLAALGDDEAPYSLEQL-----KECYRCFFVSGGL 373

  Fly   416 LPIVLLDPNESATFENFLGDSESSAKFKNLLYTNKRYHGYIEKLLPW 462
            :.:.:..|...|.. ::|.|.||..:::.:| |.|..| .:|.|..|
Worm   374 VMMPMYGPFAQAKL-SYLKDIESVQEYQEIL-TEKAEH-LMEDLERW 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	70/336 (21%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
F48G7.12	NP_503277.2	DUF1679	10..421	CDD:369592	97/437 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810