DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6834 and T16G1.5

DIOPT Version :9

Sequence 1:	NP_650104.2	Gene:	CG6834 / 41409	FlyBaseID:	FBgn0037935	Length:	895	Species:	Drosophila melanogaster
Sequence 2:	NP_506235.1	Gene:	T16G1.5 / 179775	WormBaseID:	WBGene00011799	Length:	434	Species:	Caenorhabditis elegans

Alignment Length:	396	Identity:	92/396 - (23%)
Similarity:	155/396 - (39%)	Gaps:	80/396 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 PGENYATLMLRISIDVELTDKSTKLVCFMLKVPHNVPQME-------------QMLAM-----AN 141
            |.||     |...|.::||.      |  :.|.|.|.||:             ::.||     .|
Worm    68 PNEN-----LPEKIILKLTS------C--INVHHLVSQMKEKNPDAFTEQQEAELWAMFEREAQN 119

  Fly   142 FFNSENKVYSDILPKLEELYKAKGLDITFAPKAF---KLDSVKEPKLANTVLMSDLSQDGFKNLN 203
            ..|.|..:|     ::.|.:...  |...:||.:   |.|...:   ...||..:...|..  :.
Worm   120 VHNREVNLY-----RITEKWNKN--DALLSPKIYFYKKFDCENK---TQGVLGMEYVDDAV--VR 172

  Fly   204 RLECLNLEQTKF--ALKKLAQFHAASSMNVQVNGPYEDQFVNGVMGGNKEVL---MAFYEGMVAS 263
            .|.| |.:..:.  .|:.||... |.|:::.     ||: :|.:.|.:.:.:   |...|||...
Worm   173 HLYC-NAKPHELHPILQSLATLQ-AGSLHLT-----EDE-INSISGYDFKSMVGRMMSEEGMKQM 229

  Fly   264 FRTALMANLKNFKNGEEFREKLEKAFVQIFLDFE---HLMTADPDEFNVLNHGDCWMNNLLFKLD 325
            :..|...|.:......:..|.|....|    :||   |:......:.|||.|||.|..|:|:| :
Worm   230 YTRARQINPERLTKPTDAVEALGMDIV----NFEISCHVNKYAGIQKNVLVHGDLWAANILWK-E 289

  Fly   326 SKGEVQDMLFVDFQNPKYGSPTQDLFYLILTSVHIDYKLDYFEYFIRHYHEQLTQHLDLLGFTGK 390
            :.|.......:|:|....|:|.:||..:.|:::....:..::|..:..::|...:.|:     |.
Worm   290 NDGNCVASKVIDYQLIHMGNPAEDLVRVFLSTLSGADRQAHWEKLLEQFYEYFLEALE-----GN 349

  Fly   391 Q-----PSLRELHMLMYKHGSWAVFPSIGVLPIVLLDPNESATFENFLGDSE-SSAKFKNLLYTN 449
            :     ..|:|.:.|.:..|...|.|..|  |:.....:.|...||.....| .:.|.:.|:...
Worm   350 EAPYTLDQLKESYRLYFVGGGLFVMPLFG--PVAQAKLSYSTDNENVEEYREVLTEKAERLMEDL 412

  Fly   450 KRYHGY 455
            ||:|.|
Worm   413 KRWHLY 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6834	NP_650104.2	EcKinase	95..387	CDD:281023	73/320 (23%)
CG6834	NP_650104.2	EcKinase	529..813	CDD:281023
T16G1.5	NP_506235.1	DUF1679	8..420	CDD:369592	92/396 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810