DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG18765

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001097750.1	Gene:	CG18765 / 59149	FlyBaseID:	FBgn0042110	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	109/429 - (25%)
Similarity:	199/429 - (46%)	Gaps:	72/429 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VPKWLNQTQFEELLAADVDQFSKIVGFRVK-------PAMAPGENYATLMLRISIDVELTDKSTK 103
            :|.|:.:.:.|.|: ..:.:|.||...|.|       ||:.           :.|.|.:.|...:
  Fly    16 LPTWVEKKELEALV-KQISEFRKIESLRWKWETQLAEPALC-----------VHIQVLVADNKKR 68

  Fly   104 LVSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEP 168
            .||:::|.|...| :...:.....|::|...:..:||.:||||:.....:.|.|...      :.
  Fly    69 QVSYLIKSPETVP-VGLKLPRTGDFSTERHMFEVVLPALEELYQNSDRIVHFGPPVI------QA 126

  Fly   169 KVANTVLMHDLGQN-GFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIFVNGVMG 232
            |:.::.:..|...| |:...|.|:.|::...:..|::||.:||..|.           ::....|
  Fly   127 KLKSSHIYGDYILNKGYSVANGLKGLSVTAMEGVLSKLAAYHAGTAA-----------YIAKTPG 180

  Fly   233 NNKEAIIAFMEGMLASFRTSFMANLDKFK--------NGEEYREKLEKALAGLTMEFMKLG--IV 287
            ..:| :....|...:...|:.:.:|.:.:        :..:|.:|::.     ..:::|.|  |:
  Fly   181 KIRE-LPKLRENSKSDEETAELKSLYQLRFHESLRSNDARQYEDKVKS-----FQKYVKSGTEIL 239

  Fly   288 D-PNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSH 351
            | ...||.:.:|.||.||||.::::.|:::|.:|..|...:||....||...::::..  .|.|.
  Fly   240 DSKTSFNVILNGSCWPNNLLLQVDAFGNVKDTLFSGFHTAQYGPAVYDLFSSLLTAPA--EKSSR 302

  Fly   352 FDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDN 416
            ||.:::.|.:.|:::|.:|.|.|:||||.:|...|:|||.|.......:||:||.|      |.|
  Fly   303 FDGYVKFYHDQLIENLNLLKFLGKKPSLTDLQLDLLKYGHWAFETATEILPIVLSD------FGN 361

  Fly   417 FMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455
              :|..:       |:.|....|.|..:|||::|||:.|
  Fly   362 --NDIEE-------LFRNPVFGEQIRELLPWMENRGYFE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	67/303 (22%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG18765	NP_001097750.1	PKc_like	56..323	CDD:304357	67/292 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442565
Domainoid	1	1.000	53	1.000	Domainoid score	I7597
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850