DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP007947

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_001237942.2	Gene:	AgaP_AGAP007947 / 4578412	VectorBaseID:	AGAP007947	Length:	284	Species:	Anopheles gambiae

Alignment Length:	299	Identity:	73/299 - (24%)
Similarity:	108/299 - (36%)	Gaps:	100/299 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   605 LLLENLQPSGFKMV--DRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTA 667
            |:||||:..||:.:  |.....|.||.||.|..||::|:|::..::..|...|....|:. |:.|
Mosquito     5 LVLENLKTQGFETIPSDATRTFDEEHIKCALAALARFHSATILLEKETGTSVPLQFPGLL-EENA 68

  Fly   668 PIFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAF-NVLNHGDAWIN 731
            .|.:.   |..:  |||                 |:..||.:|        || :..||
Mosquito    69 WIRRD---NNPR--IEE-----------------LNIAVDILL--------AFVSCYNH------ 97

  Fly   732 NIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAK 796
                    :.||...||..::..|.......|      |:....|:.:.:.||    |..|...:
Mosquito    98 --------ELRVHRKLLKPNEEKKNAKRENSL------SSVSKRKLTKLEPLI----QQQKFQCE 144

  Fly   797 LLNYNGFI--PSLKE----LHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEEN---- 851
            |.. |.|.  .|||:    |||.:.||          ...:| |:|         .|.|::
Mosquito   145 LCG-NRFTRKSSLKDHKLILHAGVKQH----------CCKIC-NRT---------FGREDSLNTH 188

  Fly   852 -----GKSLREAMFSNERYRANI------ERVMPWINRR 879
                 ||..|..:.|....:.|.      |..||...|:
Mosquito   189 MALHVGKKFRCKLCSKSFAKGNFLRKHLEEHEMPDSKRK 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	49/197 (25%)
AgaP_AGAP007947	XP_001237942.2	PKc_like	<3..>67	CDD:304357	22/62 (35%)
		COG5048	<96..267	CDD:227381	39/177 (22%)
		C2H2 Zn finger	143..164	CDD:275368	6/21 (29%)
		zf-C2H2_6	170..192	CDD:290623	6/41 (15%)
		C2H2 Zn finger	172..192	CDD:275368	5/29 (17%)
		C2H2 Zn finger	199..219	CDD:275368	2/19 (11%)
		C2H2 Zn finger	230..250	CDD:275368
		C2H2 Zn finger	258..278	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900