DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP003765

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_001230752.2	Gene:	AgaP_AGAP003765 / 4577157	VectorBaseID:	AGAP003765	Length:	412	Species:	Anopheles gambiae

Alignment Length:	446	Identity:	114/446 - (25%)
Similarity:	191/446 - (42%)	Gaps:	62/446 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   464 ELLAALKPQQPQPENTDQIPDWLNIDDFKEIILSAEPNFEKILSSTSKLAT---KPGDNFASKLL 525
            |....:||..|        |:|:.....:.|:...|.  :|.|..|...:|   |||:..||:|.
Mosquito     3 ETAPEVKPASP--------PEWVTSGYLETILRKFEG--DKDLHVTDMESTPVGKPGEYLASQLF 57

  Fly   526 KVEI--------EAQLKDNSVKTFSYILKVHSDNDAI-NFSDFNLFPKEIEVYSTYVPAFERFYK 581
            :|.:        |....:.|.|  ..::|:..|...: :..|..||..|:::|...:|..||...
Mosquito    58 RVTVHYRGTKRNETDGGEGSAK--KLVIKIQPDKGVMADTMDGTLFKTELKMYGEILPKMERLLA 120

  Fly   582 DVGLPVTFSPKSFRLSKDVSKEYLLLENLQPSGFKMVDRMIGMDL----EHSKCTLKKLAQWHAA 642
            |...||.. ||...:|. ..:..::||:|.|.|:|      |.||    |..|.....:|::|||
Mosquito   121 DNERPVPL-PKCVHVSA-TPQPIIVLEDLAPDGWK------GHDLIESFEEVKPITIAIARFHAA 177

  Fly   643 SLKYKELNGPYSPKYNNGIFTEQTAPIFKGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVD 707
            |. |...|.....::...:| :...|:.:.||.|..|:|||.:..:.|.:.::.........|.|
Mosquito   178 SF-YLSKNKTDFEEFQTDLF-KNKHPVLEWMFGNNLKAFIESLRTWSGCERFVEPFERAYADYCD 240

  Fly   708 RILED---AKINEQAFNVLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMS 769
            | |.|   .|...:.:|||||||....|::.|:..:|.:.|:..||.|...:..||.||||.:.:
Mosquito   241 R-LHDIYCCKTPGRLYNVLNHGDFHAKNLLHQFNDEGGIAESRFLDFQACCWSTPAIDLYYLLNN 304

  Fly   770 STQLDIKVDQFDYLIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLN 834
            .....:|....:.::.:||.......|.:.|.|:||::.:|...|:::....    :...:..|.
Mosquito   305 IVHYKVKAAHKEEIVSFYHAEFTAALKAIGYLGYIPTMIDLQIELLRNGFLD----ILHYTCFLQ 365

  Fly   835 KTTDDFT-------TDSFLGNEENGKSLREAMFSNERYRANIERVMPWINRRGLLD 883
            ....|||       ....:||         ....:|.|:..::.::|....:|||:
Mosquito   366 FRFFDFTKIPPEKLATGQVGN---------LGLESEEYQTLMKSLIPGYVYKGLLE 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	83/299 (28%)
AgaP_AGAP003765	XP_001230752.2	PKc_like	48..335	CDD:304357	83/299 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810