DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CHKov2

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651387.1	Gene:	CHKov2 / 43068	FlyBaseID:	FBgn0039328	Length:	409	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	143/431 - (33%)
Similarity:	222/431 - (51%)	Gaps:	52/431 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PKWLNQTQFEELLAADVDQFSKIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFMMKV 111
            |:|:.:..|..||......|..|:.|....|::.||||.|::|||.|:::|.|.|.:.||:::|:
  Fly     7 PQWVTKELFSSLLEQSNRNFKAIIKFVPTSAISKGENYLTIVLRIQIEMQLKDNSIEDVSYILKI 71

  Fly   112 PHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDI--KFAPRAFKLDATKEPKVANTV 174
            |. .|: ::.......|.:|...|..::|::|:|| ||...|  ||.|...|...  ||..::.:
  Fly    72 PL-VPE-DEKNDFHEMFDAELDMYDHLIPELEDLY-AKNTSISPKFKPVHLKFPG--EPVKSDYI 131

  Fly   175 LMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPY-PDIFVNGVMGNNKEAI 238
            |:.||.:.|::|.:|.:.|...:.:..|.:|||:|||.|..|...|.| .||         :|:.
  Fly   132 LLEDLRKKGYRNADRTQGLEQFEVEAVLKKLAQWHAASAKRVVELGEYEKDI---------RESY 187

  Fly   239 IAFMEGMLASFRTSFMANLDKFKNG---------EEYREKLE-----------KALAGLTMEFMK 283
                      |.|.....||:|...         ::|  .||           ..|..|.:||
  Fly   188 ----------FTTEHQKLLDEFNINFCMPFLECMQQY--NLEPGQLVLISDYTSQLTDLNIEF-- 238

  Fly   284 LGIVDPNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYK 348
             |..||.|.:.|||||.|.||.:||..::.::||:.|||||.||||:||.|||..:::|.:...|
  Fly   239 -GKNDPLELSVLNHGDFWCNNFMFKYKNASEVEDVCFVDFQLPKYGTPAQDLLCILMTSPKFSIK 302

  Fly   349 LSHFDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSAT 413
            |..||:||.:|.:.||:||.:|.:....|:|.:.|..|.:|..|.......:||:|||.|...:.
  Fly   303 LDKFDYFIEYYHQQLVEHLTMLNYNRNAPTLSKFHAHLHRYSLWAFICAQRMLPIVLLPPDVDSH 367

  Fly   414 FDNFMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFL 454
            ..|.|.:|.:.::|:..::......:.|:.|||||.|||::
  Fly   368 IGNVMGNSEEAIAFKRKMFLLPAYVDQIKVILPWLINRGYI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	109/314 (35%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CHKov2	NP_651387.1	EcKinase	40..326	CDD:281023	109/314 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442579
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950