DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG10559

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651382.2	Gene:	CG10559 / 43063	FlyBaseID:	FBgn0039323	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	146/411 - (35%)
Similarity:	244/411 - (59%)	Gaps:	13/411 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VPKWLNQTQFEELLAADV-DQFSKIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFMM 109
            :|.||....|||||:... ..::.|..|:.:..:.|||||:|:|||:.::|||.|.:.:.||:|:
  Fly    10 MPTWLRANLFEELLSKRYGGNYAGIKSFKPEAGLKPGENYSTIMLRLKLEVELQDHTIENVSYML 74

  Fly   110 KVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVANTV 174
            |.|:|.....:::...|.|..|...:.:::|::|::||..|:::||..:|:::||..:     .|
  Fly    75 KTPYDFEMYREILRKNNMFAVERDVFIQVIPELEQMYKDVGVEVKFGAKAYEIDAPDD-----YV 134

  Fly   175 LMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPDIFVNGVMGNN-KEAI 238
            |:.|||..||:|::|||.|::..||..|.::||:||..||.:.:.||||..::.....:. ||:|
  Fly   135 LLQDLGPLGFRNVDRLEGLDMVHTKCVLKKMAQWHAVSATRIHLKGPYPQNYLQPTYADTMKESI 199

  Fly   239 IAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMKLGIVDPNEFNALNHGDCWMN 303
                |.:..:....|:..|..::..|||...:.|....:......:...||.:||||||||||.:
  Fly   200 ----EQVAETLGKYFLKCLPLYEGYEEYSAAVHKMQPKIVDLMYAMNTPDPQDFNALNHGDCWTS 260

  Fly   304 NLLFKM-NSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFFIRHYQEALVKHL 367
            |::||. :.|.:..:..|||.|.||..|.|.||:||::.|.:.:.:||.||:||::|.:.||:||
  Fly   261 NIMFKYEDESPEPIETYFVDLQLPKVTSVAYDLIYFLLGSTKFEIQLSQFDYFIKYYHDHLVEHL 325

  Fly   368 GILGFTGRK-PSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNFMSDSADGVSFRGSL 431
            .:|.:...| |:|..||..|:|||.........:.|.||||.|:.|...:|::::.:|...:.::
  Fly   326 RMLNYPEAKTPTLGFLHTQLLKYGRVGYHIAFILCPPVLLDRTEDANLTDFVTETDNGDGLKLAM 390

  Fly   432 YANKRCQEYIERILPWLDNRG 452
            |:|.|.::::..||.||:|||
  Fly   391 YSNARYKKHVSAILKWLNNRG 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	108/293 (37%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG10559	NP_651382.2	EcKinase	45..330	CDD:281023	108/293 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442529
Domainoid	1	1.000	57	1.000	Domainoid score	I17979
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.950