DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG10550

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651380.2	Gene:	CG10550 / 43061	FlyBaseID:	FBgn0039321	Length:	425	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	154/426 - (36%)
Similarity:	248/426 - (58%)	Gaps:	19/426 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   467 AALKPQQPQPENTDQIPDWLNIDDFKEIILSAEPNFEKILSSTSKLATKPGDNFASKLLKVEIEA 531
            :|.||..|....  .||.|:|.:.|:.||.....||:||::.....||.||:|:.|.:::|.::.
  Fly     6 SAEKPVNPNEHL--HIPKWINEEYFQPIIEKDVENFDKIINLVPIAATAPGENYTSIMIRVIVDI 68

  Fly   532 QLKDNSVKTFSYILK--VHSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSF 594
            .|||.|.:..|||||  :.:|:.|.......|||||.::|..::|.|.:.||:.||.:..:||.
  Fly    69 LLKDGSEQRVSYILKTMLEADSGADVIDGMGLFPKERKMYEVHIPQFVKLYKEAGLEIELAPKC- 132

  Fly   595 RLSKDVSKEY--LLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKY 657
             |..|.:.|.  ::.|:|....||..||:.|.||.|.:..|:|||:.||||:..||:||||...|
  Fly   133 -LHVDATDELITMVFEDLSRQNFKNFDRLKGFDLPHMREVLRKLAELHAASVVAKEINGPYDAMY 196

  Fly   658 NNGIFTEQTAPIFKGMFVNTKKSFIEEVSKFD--GVDEYLHKMPEILDTYVDRILEDAKINEQAF 720
            |..|:.||:..:|:.:....::.|::.:..:|  ..:.|:.:|.:.|:.: :..::..:::|..|
  Fly   197 NMSIYNEQSRDLFESLGKQREEQFLKAMRNWDLENAESYIARMWDPLEVF-EEAVQVNQVDEDEF 260

  Fly   721 NVLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIR 785
            |||||||.|.|||||.|:.:|.:..|:|:|.||.|:|:|||||:|.|.:|..||||:.:||:.|:
  Fly   261 NVLNHGDCWSNNIMFNYKDNGEIDRTILVDLQVGKWGSPAQDLWYLITTSASLDIKIKEFDHFIQ 325

  Fly   786 WYHQNMKEHAKLLNYNGFIPSLKELHAILIQH----PIFAAGTVLTTLSMCLNKTTDDFTTDSFL 846
            .|||.:.|..|||||:..||:|::||.:::::    |:.|.|.::.||.    .|..|......|
  Fly   326 IYHQRLAECLKLLNYSKPIPTLRDLHIMMLKYGFWGPLTAMGVMVATLM----PTDKDANMKMIL 386

  Fly   847 GNEENGKSLREAMFSNERYRANIERVMPWINRRGLL 882
            .......::|...|.|..|...::.::|:.:.:|||
  Fly   387 AQGPEADAIRYRTFINPYYAKAMKVLLPFFDNKGLL 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	114/289 (39%)
CG10550	NP_651380.2	EcKinase	53..340	CDD:281023	114/289 (39%)
CG10550	NP_651380.2	APH	108..338	CDD:279908	91/232 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442527
Domainoid	1	1.000	207	1.000	Domainoid score	I6156
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850