DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6830 and CG13658

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651374.2	Gene:	CG13658 / 43055	FlyBaseID:	FBgn0039315	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	424	Identity:	102/424 - (24%)
Similarity:	183/424 - (43%)	Gaps:	41/424 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SKQAPKAQVNPEPPAPPNKPEPEVDHSDLVPKWLNQTQFEELLAA-DVDQFSKIVGFRVKPAMAP 80
            ::....||.|.:          |||    .|.|||....|..|.| :.|....:...::.||...
  Fly     2 AENVDSAQFNAD----------EVD----APAWLNAELIEGALRAYEKDPELHVTDLKISPATLQ 52

  Fly    81 GENYATLMLRISIDVELTDKSTKLVSFMMK-VPHDTPQMEQMMSMANFFTSENAAYTEILPKMEE 144
            |::||::|.| ::....|.|.....:.::| :|......:.|:|.:..|.:|...|::.||::|.
  Fly    53 GDHYASVMFR-AVSHYSTAKGNFSKALIVKTMPEQEGHKKDMLSNSPIFKTEILMYSKALPELER 116

  Fly   145 LYKAKGLDIK-FAPRAFKLDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQF 208
            :.:..|...| :||..:.   :.||.  ..::..||...|: .:.|....|.|:.:.|..:||::
  Fly   117 ILREAGDTTKLYAPCIYH---SLEPH--QVMIFEDLVPQGY-TVIRDRYPNKEELQKAFFKLAKW 175

  Fly   209 HAAGATMVQVHGPYPDIFVNGVMGNNKEAIIAFM-EGMLASFRTSFMANLDKFKNGEEYREKLEK 272
            |||...::.....:...|..|:.|     :..|: :.::.:....|:..|||.....:|:...||
  Fly   176 HAASMKVLNERPDFLKEFKYGLWG-----MPNFLNDSIVTTGVPCFLEMLDKVPELTKYKPYFEK 235

  Fly   273 -------ALAGLTMEFMKLGIVDPNEFNALNHGDCWMNNLLFKMN-SSGDLEDMVFVDFQNPKYG 329
                   .::.:..|:..  ...||.:..|.|||....|::|:.| .:|..||::.||||.....
  Fly   236 IKDNYIQQMSAVMEEYRT--NPKPNRYYVLCHGDFHGRNMMFRYNKETGSFEDVMLVDFQISNVC 298

  Fly   330 SPAMDLLYFIISSVQIDYKLSHFDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVL 394
            ..::||:|.|...:..:.:......:|.:|...|...|..:||.|..|:...:...:..:..:..
  Fly   299 PLSIDLIYSIFMVMDTEDRWDLGKEYINYYFSVLADTLKKIGFKGEMPTQTGVWEHIHGHKDYEF 363

  Fly   395 FPTISVLPLVLLDPTQS-ATFDNFMSDSADGVSF 427
            |...|.||||....|:: .:.|:|........||
  Fly   364 FMMTSFLPLVAAMNTKTFKSMDSFFDPQTKQKSF 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	71/302 (24%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG13658	NP_651374.2	EcKinase	52..341	CDD:281023	71/302 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840