DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG31104

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_733090.1	Gene:	CG31104 / 43054	FlyBaseID:	FBgn0051104	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	407	Identity:	104/407 - (25%)
Similarity:	178/407 - (43%)	Gaps:	55/407 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   478 NTD--QIPDWLNIDDFKEIILSAE--PNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSV 538
            |.|  |.|.|||.....:|:...|  |:. |:.......||..||::||.:.:.::|......
  Fly     9 NADELQAPAWLNAQFIGDILREYEQLPDL-KVTDLQVSPATAQGDHYASVMFRTKVEYTTPKG-- 70

  Fly   539 KTFS-YILKVHSDNDAIN---FSDFNLFPKEIEVYSTYVPAFERFYKDVG-LPVTFSPKSFRLSK 598
            |.|. .|:|...:.:...   .|:.:||..||.:|...:|.|||..::.| ....|.|..:...|
  Fly    71 KFFKPLIIKTMPEQEGHKKDMLSESHLFETEIGMYCHALPEFERILREAGDNTKLFVPCIYHSLK 135

  Fly   599 DVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIF- 662
              .::.::.|:|.|.|:.:: |.....|...|....|||:|||.|:|.......:..::..|:|
  Fly   136 --PRQVMIFEDLVPQGYTVI-RDSPPSLGDLKLAFDKLAKWHAVSMKVINEQPYFLKEFQYGLFE 197

  Fly   663 --TEQTAPIFKGMFVNT-KKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINE------- 717
              |..|.|     |:.| ..:|||.:.|...:.:|.|...:|.|.|:.|:  :.:::|
  Fly   198 MPTIDTDP-----FITTGMTNFIEMLDKMPELRKYKHHFEKIKDNYMQRL--EVEMHEYHKYRRN 255

  Fly   718 QAFNVLNHGDAWINNIMFQYESD-GRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFD 781
            ..:.||.|||..:.|:||::..: |...:.:|:|.|::.......||.|.:....:.:.:.:..:
  Fly   256 DRYYVLCHGDFHLRNMMFRHNKELGAYDDVMLVDFQLSNLCPITVDLTYSVYMLMEPEQRWEMGE 320

  Fly   782 YLIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFL 846
            .||..|...:....:.:.|.|.:|:.:||.. .||:                ||..|.|...:||
  Fly   321 NLINEYFSVLVATLRKIGYKGDMPTQRELWE-QIQN----------------NKYYDFFLISTFL 368

  Fly   847 ----GNEENGKSLREAM 859
                |.:.|...:.||:
  Fly   369 PIMVGVKSNDLKMHEAL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	74/300 (25%)
CG31104	NP_733090.1	EcKinase	50..339	CDD:281023	74/300 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930