DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG10513

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_651370.2	Gene:	CG10513 / 43051	FlyBaseID:	FBgn0039311	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	130/426 - (30%)
Similarity:	214/426 - (50%)	Gaps:	47/426 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 PDWLNIDDFKEII--LSAEPNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKD--NSVKTFSY 543
            |:||:....:.::  |..:|.. :|.....|.||..|||:||.:.:|.| ..||.  .|.:|..|
  Fly    16 PEWLDETYLERLLRDLKNDPGL-RITDLVIKPATAKGDNYASVMTRVRI-LFLKSGAKSPETEYY 78

  Fly   544 ILKVHSDNDAIN---FSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKEYL 605
            |:|...:|||..   ||.:.:...|:.:|...:|......:....|.....|:  |..|...|.:
  Fly    79 IVKTTYENDAFASGIFSQYQVSTTEMRMYEKILPQLSSLIEKTRQPEKVFAKT--LHVDYEHEAI 141

  Fly   606 LLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTAPIF 670
            :.|:|..:.:.:.||::|.||||::..|:|||:.|||:....|.......|:::|||...| ..|
  Fly   142 IFEDLAVTKYVLADRLVGFDLEHTRLGLRKLAKMHAAAAVLNERQPGLLTKFDHGIFNRHT-QAF 205

  Fly   671 KGMFVNTKKSFIEEVSKFDGV-DEYLHKMPEILDTYVDRILEDAKINEQA--------------F 720
            ...||||.           || .::..:.||:.:.|..::   .|:.|:.              |
  Fly   206 APFFVNTV-----------GVAADFARECPELGERYATKL---KKLQERVMEYSTRVYDPQPGDF 256

  Fly   721 NVLNHGDAWINNIMFQYESDGRVKETL---LLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDY 782
            |.|.|||.|:||:|.:|   |..||.|   |:|.|...:.:||.||:||..:|.|:||:.:|.|.
  Fly   257 NTLVHGDYWVNNVMLRY---GENKEPLDMTLIDFQFCSWSSPAVDLHYFFNTSVQVDIRYEQQDA 318

  Fly   783 LIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLG 847
            |.::||..:.|..|.||:.|:||:|::....|.:...||....|...::..|....|...::.:.
  Fly   319 LFQYYHTVLVETLKDLNFGGYIPTLRQFVLQLERGRFFAVTVALVCQAILTNDQNADADFNALMK 383

  Fly   848 NEENGKSLREAMFSNERYRANIERVMPWINRRGLLD 883
            ::|.|::.|:.:::|:|.:.|::|.:|..:|.||||
  Fly   384 DDERGRNFRKVLYTNKRLQDNLKRELPRFDRSGLLD 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	97/306 (32%)
CG10513	NP_651370.2	EcKinase	50..336	CDD:281023	97/306 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850