DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG11889

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001287526.1	Gene:	CG11889 / 3772506	FlyBaseID:	FBgn0039308	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	115/432 - (26%)
Similarity:	202/432 - (46%)	Gaps:	30/432 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 PEPEVDHSDLVPKWLNQTQFEELLAA----DVDQFSKIVGFRVKPAMAPGENYATLMLRISIDVE 96
            || :..|:  .|.||.:...|:.|..    |.....|:.   :|||.|.|||||::|.|||::..
  Fly     2 PE-KTTHN--APAWLTEEYVEKKLRVYFKNDTLNLKKLT---IKPATANGENYASVMTRISVEYI 60

  Fly    97 LTD-KSTKLVSFMMKVPH-DTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRA 159
            ..| |..:..:|::|... |......::.....:|.|...|.:|||::.::.|.:..|.:
  Fly    61 TKDSKDNQSATFLLKTTFADKDPAAHLLINYGIYTREIDMYEQILPRLADIVKNELHDSR----- 120

  Fly   160 FKLDATK--EPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPY 222
             ||.|..  ..:..::::..||....:|...|::.|:||.|...|.:||.||||||.:.|   ..
  Fly   121 -KLFAATVGVDRERDSIMFEDLSLERYKVACRVKKLDLEHTYLVLEKLADFHAAGAALAQ---RQ 181

  Fly   223 PDIFV----NGVMGNNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMK 283
            |.||.    .|....:.......|:.:|.:...:...:.|.   .|.|:.|:::.:..:.....:
  Fly   182 PGIFEKNYDRGFFNKHVRGYEPIMKNILKALSRTLDLSPDL---KERYQAKIDRLIDNVMDYGER 243

  Fly   284 LGIVDPNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYK 348
            ...|.|.:|..|.|||.|..|::|:.:..|...:.:|:|||...:.|||:||.||..:|:..:.:
  Fly   244 STSVAPGDFVTLAHGDIWTTNVMFQYDDEGHPVNAIFIDFQFSVWNSPAIDLQYFFSTSIHENLR 308

  Fly   349 LSHFDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSAT 413
            |......::.|...||..|..:.::|:.|||.|..:.....|.:.:|.::...|.::.:..:..:
  Fly   309 LERQTELVQFYFYKLVVALERVKYSGKVPSLFEFQQQFRTKGFYAVFASLIFEPTMVYNGKEEPS 373

  Fly   414 FDNFMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455
            .:.||:....||..|.::|..:...:.:...||:||..|.|:
  Fly   374 IEQFMTSDEKGVRLRDAVYQTEENLKKLHLTLPFLDQLGLLD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	81/299 (27%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG11889	NP_001287526.1	EcKinase	44..332	CDD:281023	81/299 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459372
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940