DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG16898

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_611452.2	Gene:	CG16898 / 37276	FlyBaseID:	FBgn0034480	Length:	407	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	120/433 - (27%)
Similarity:	205/433 - (47%)	Gaps:	48/433 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LVPKWLNQTQFE-ELLAADVDQFSKIVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFM 108
            ::|.||.:...: :|.|...|...|:|....|||...|:||.:||.||.::::..|...:..:::
  Fly     1 MLPNWLTEEYLQPKLRAYYKDDQLKVVKVWAKPATEKGQNYMSLMTRIHVEIQQGDGLLQNRTYI 65

  Fly   109 MK--VPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVA 171
            :|  :..|.||.:..:.. :.:..|...|..|||||.||.:..||..||......:|     :..
  Fly    66 IKESLSEDCPQAKVFLEY-DVYNREMDMYEFILPKMNELLQEVGLTGKFTADTIFVD-----REY 124

  Fly   172 NTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPYPD-----IFVNGVM 231
            .|:::.||.|..:.|.:|::.|:|..||..|..||:||||...:.|.|   |:     :|::...
  Fly   125 RTIILEDLAQYNYVNADRVKQLDLAHTKLTLEVLAKFHAASIVVKQRH---PELLTKSLFIHCFS 186

  Fly   232 GNNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMKLGI----VDPNEF 292
            .:|| ......||:|::| ..|:......|  ::|..||:|    :....|..|.    |...|.
  Fly   187 RDNK-GYTEVYEGVLSAF-IRFINEQPVLK--KKYGNKLQK----IHENIMDYGARTFEVGEQEL 243

  Fly   293 NALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHFDFFIR 357
            ..|:|||||..|.|::.:.:.:.:..|.:|||...:.||..||..|...|:: |.........:.
  Fly   244 LTLSHGDCWTTNFLYQYDDASNPQSAVAIDFQFSNFTSPVNDLHQFFTVSLR-DEVQDMESVLVE 307

  Fly   358 HYQEALVKHLGILGFTGRKPSLRELHR--------TLIKYGGWVLFPTISVLPLVLLDPTQ-SAT 413
            .|...|..::..|.:.|..|||:...:        .|:.:    ||.     |:::.|.|: |:.
  Fly   308 KYYSDLKTNVDTLSYKGIFPSLQGFQKQFESRRFMCLLAH----LFK-----PVIIYDGTEVSSD 363

  Fly   414 FDNFMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLEV 456
            |.:...|:.:|:.|:.::|||:|..:...::|..||.:|.|.:
  Fly   364 FSSVYKDTEEGIRFQKAIYANERVLKSATKLLAMLDAKGVLNL 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	85/302 (28%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG16898	NP_611452.2	EcKinase	37..322	CDD:281023	85/302 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459404
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850