DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG9497

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001260130.1	Gene:	CG9497 / 33884	FlyBaseID:	FBgn0031800	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	103/417 - (24%)
Similarity:	196/417 - (47%)	Gaps:	29/417 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 PDWLNIDDFKEIILSAEPNFE-KILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKTFSYILK 546
            |..|::..|:|::.:|..... ::||...::.:..|:|:.|::.:|::..:..|:..:..::|:|
  Fly    14 PSHLDVPFFEEVLETALRTARVQLLSIHIRMGSSTGENYCSQIYRVKVSFKRPDHPEQHMAFIVK 78

  Fly   547 VHSDNDAINF-SDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKEYLLLENL 610
            .....|::.| .|..::.||...|...:|..|...:   ....|.||.:...|. .:..|:.|:|
  Fly    79 SIPHLDSVEFIDDLQVYLKEKITYYEVLPRLELLMQ---CNRRFGPKLYHYLKQ-PENSLVFEDL 139

  Fly   611 QPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTAPIFKGM-- 673
            ...||.|..|.:|::.||.:..:::||::||.|:....::......|.:|:.:.:......|:
  Fly   140 AEKGFVMASRELGLNEEHCQLVMERLAEFHATSMALAVVDPHIFDAYGDGMLSPRGLAKDDGLLM 204

  Fly   674 --FVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDAWINNIMFQ 736
              |....|.....||.:.|.::...|:.:.:......:.......|:...||||||.|:||::|:
  Fly   205 QFFSGNGKELHHLVSTWPGFEKIAEKIGKYMQNQRANLERSQAPQEKEVKVLNHGDLWVNNMLFK 269

  Fly   737 YESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLLNYN 801
            |:...|.::.:|:|.|::.:|:|..||.||..:|..|::...:...|:|.||..:.:....|:..
  Fly   270 YDGAQRPQDLILIDFQLSVWGSPGIDLNYFFYTSLTLEVLRHRRTQLLRTYHARLAKTLLDLDMG 334

  Fly   802 GFIPS----LKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDSFLGNEENGKSLREA---- 858
            ..:||    |:|:|. ...:..||:..:..|:|....:|.|:        |.||.|....|
  Fly   335 IPVPSYEQILEEVHR-RESYGFFASYGIFPTVSQDKAQTADN--------NLENFKDADFAKQKV 390

  Fly   859 --MFSNERYRANIERVMPWINRRGLLD 883
              ||.:.|....:...:|...|.|:||
  Fly   391 RQMFQSRRLADTLRYTLPHFERAGVLD 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	72/288 (25%)
CG9497	NP_001260130.1	EcKinase	49..331	CDD:281023	71/285 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459270
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850