DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and CG33511

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001014492.2	Gene:	CG33511 / 3346223	FlyBaseID:	FBgn0053511	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	104/477 - (21%)
Similarity:	188/477 - (39%)	Gaps:	135/477 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 LLAADVDQFSK-IVGFRVKPAMAPGENYATLMLRISIDVELTDKSTKLVSFMMKVPH-DTPQMEQ 120
            |:.:.||..|| ::|:.       ||.|   .|.:..:|:...|...|..|:..:|. :.||.|:
  Fly    27 LINSQVDAGSKDLMGYM-------GEYY---KLHLEAEVKGDKKKYFLNYFIKSLPRKNEPQREE 81

  Fly   121 MMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRAFKLDATKEPKVANTVL-MHDLGQNGF 184
             ......|..|:|.|::||||::: |..|    |..|:.:        ...|.:| :.||.|: :
  Fly    82 -CERKGVFQKESALYSQILPKIQK-YATK----KLYPKCY--------YSRNDILVLEDLTQD-Y 131

  Fly   185 KNINRLECLNLEQTKFALTRLAQFHAAGATM-----VQVHGPYPDIFVNGVMGNNKE------AI 238
            :::...|...|:..|..|..|::.|||....     |:::..|.::.:...:.:|..      ..
  Fly   132 RHLRANEYYTLDHYKIVLEHLSELHAASIAWEEKENVKIYESYKNVLIELHLDSNNSWYITGLKA 196

  Fly   239 IAFMEGMLASFRTSFMANL--DKFKNGEEYREKLEKALAGLTMEFMKLGIVDPNEF--NALNHGD 299
            |.|:......|:|....|.  ||..|.....|:|                |.|::.  |.|.|.|
  Fly   197 IVFLAARNPHFQTMKAQNFIQDKLYNLLTKAEEL----------------VAPSKTIRNVLCHRD 245

  Fly   300 CWMNNLLFKMNSSGDL--EDMVFVDFQNPKYGSPAMDLLY--FIISSVQIDYKLSHFDFFIRHYQ 360
            .|.:|:::..|....:  .....||||..:|.||.:|:|:  :|::|.::  :.:.:|..:.||.
  Fly   246 TWDHNIVYYFNKESSVLPNACCIVDFQLTQYCSPTLDVLFLLYIVASAEV--RRAIYDECLEHYY 308

  Fly   361 EALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNFMSDSADGV 425
            :.|..||..||          |.:.||                         |.:||
  Fly   309 KNLQHHLDRLG----------LDKNLI-------------------------TENNF-------- 330

  Fly   426 SFRGSLYANKRCQE-YIERILPWLDNRGFLEVSTDP---LPPELLAALKPQQPQPENTDQIPDWL 486
                    .|.||. .:..::.|        ..|:|   :.|.:...|:.::|     ::...:|
  Fly   331 --------RKECQRTRLAALVIW--------ALTEPQTKMSPSISNRLRSEEP-----EKFDYYL 374

  Fly   487 NIDDFKEI--ILSAEPNFEKIL 506
            |.|..:.:  ::..:|.:|:.:
  Fly   375 NCDRSELLLRVIEIQPGYEETI 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	77/312 (25%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
CG33511	NP_001014492.2	PKc_like	41..319	CDD:304357	77/320 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459716
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940