DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP003760

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_559536.2	Gene:	AgaP_AGAP003760 / 3290897	VectorBaseID:	AGAP003760	Length:	406	Species:	Anopheles gambiae

Alignment Length:	362	Identity:	98/362 - (27%)
Similarity:	171/362 - (47%)	Gaps:	42/362 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   478 NTDQI--PDWLNIDDFKEIILSA--EPNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNS- 537
            |.|::  |.|||.:.|::::..:  :|..|.|.....:..|..||::||.:.:..:..:.:.:|
Mosquito     3 NQDELEAPGWLNDEFFRDVMRESNNDPTIELIKPCVLRPGTNKGDHYASVMFRTTVTYRSQRSSE 67

  Fly   538 VKTFSYILKVHSDNDAIN---FSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKD 599
            .::.:.|:|..|:.|.:.   ..|..||..|||:||..:|...|..|::|....:....|...|
Mosquito    68 EQSANIIMKTKSEADGLKKELLDDDRLFAIEIEMYSKVLPEMTRMLKEIGEEYKYPRYIFGALK- 131

  Fly   600 VSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTE 664
             ....|:||::...|:.|.|.:  .:|:..|..:|.:|.:||||:..:..:..::.::...:..:
Mosquito   132 -PHTILILEDISDQGWVMGDLI--NNLDDMKPIVKDIAMFHAASVMLESADSTFAERHAYSMSDK 193

  Fly   665 QTAPIFKGMFVN--------TKK-----SFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKIN 716
            ...  |:||...        ||:     .|.:.:.||         ...:.:.||...::...|.
Mosquito   194 FVG--FEGMITKGFGDLMHLTKRYPEFAHFAKPLQKF---------QDSLRELYVSSYIQSKTIQ 247

  Fly   717 EQAFNVLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFI-MSSTQLDIKVDQF 780
                |||.|||....|::.|.::.||..:|:|||:|:..:..||.|:||.: |..|| .:|....
Mosquito   248 ----NVLIHGDFHGKNMLHQVDAKGRHTDTILLDYQICCWTTPAVDVYYLLDMIPTQ-KVKDKHR 307

  Fly   781 DYLIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQH 817
            ..||..|:|...:..|.|.|.|.||||.:|...|::|
Mosquito   308 SELIYMYYQQYSDLLKRLGYVGKIPSLLDLQIELLRH 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	78/301 (26%)
AgaP_AGAP003760	XP_559536.2	PKc_like	45..327	CDD:304357	78/301 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810