DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6830 and AgaP_AGAP003757

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_559533.6	Gene:	AgaP_AGAP003757 / 3290895	VectorBaseID:	AGAP003757	Length:	423	Species:	Anopheles gambiae

Alignment Length:	429	Identity:	118/429 - (27%)
Similarity:	214/429 - (49%)	Gaps:	31/429 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   476 PENT--------DQIPDWLNIDDFKEIILSAEPNFEKILSSTSKL----ATKPGDNFASKLLKVE 528
            ||||        ...|||||....::::..|   |:.......||    |...|:|:||.:.::.
Mosquito     2 PENTIPACLNASADAPDWLNEAYVEQMLRCA---FKDASIKVRKLDVYYAVPKGNNYASIIFRIG 63

  Fly   529 I--EAQLKDNSVKTFSYILKVHSDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSP 591
            :  .:||:....:||.....:...........:::..||::||...:|..:...|.:|.|....|
Mosquito    64 VTYHSQLQYEIARTFIVKGMITEGIAGEKLRQYDVQRKEMDVYQFVIPELKLLMKSIGEPGELYP 128

  Fly   592 KSFRLSKDVSKEYLLLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPK 656
            .:  |..|..:|.::.::|.|.|::||||..|||:.|.|..:|.:|:.||:|||.:|........
Mosquito   129 TA--LIVDRKREVIVFKDLTPDGYRMVDRTQGMDMVHMKMAIKLMAKMHASSLKMREQQPNIFVP 191

  Fly   657 YNNGIFTEQTAPIFKGMFVNTKKSFIEEVSKFDGVDEYLH-KMPEILDTYVD---RILEDAKINE 717
            ||..|.|.:| ..|..|||:...:..:||.|:....:|.| |:.::...:|:   |:::    |:
Mosquito   192 YNTCIVTRET-DAFYPMFVHIFNALTDEVGKWGSEWKYYHEKLQQLAPNFVEYSQRVVD----ND 251

  Fly   718 QAFN---VLNHGDAWINNIMFQYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQ 779
            .|.:   |...||.|:||.:::|:..|...:.:|||.|...||.|..|..|...:|.:.||:.:.
Mosquito   252 PASDDLCVFVQGDMWVNNFLYKYDGQGNPIDAVLLDFQYCTYGTPMIDFCYLYYTSARDDIRQNC 316

  Fly   780 FDYLIRWYHQNMKEHAKLLNYNGFIPSLKELHAILIQHPIFAAGTVLTTLSMCLNKTTDDFTTDS 844
            ||.|:::|:..:.::|:.|.|...:|:|.:......:...:|..:....|.:.:|..|.|...::
Mosquito   317 FDELLQYYYYQLVDYARRLQYRARLPTLYQFLQQTQRKMFYAVYSTFIALPVQMNDNTADADFEA 381

  Fly   845 FLGNEENGKSLREAMFSNERYRANIERVMPWINRRGLLD 883
            .:.|:|..:|.:..:.:|::|:..:..::|..:|:||||
Mosquito   382 LMCNDERAQSFKRMIVANDKYQTILRGLLPQFDRKGLLD 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	85/292 (29%)
AgaP_AGAP003757	XP_559533.6	EcKinase	51..337	CDD:281023	85/292 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820