DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6830 and CG31099

DIOPT Version :9

Sequence 1:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_733099.1	Gene:	CG31099 / 326117	FlyBaseID:	FBgn0051099	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	127/409 - (31%)
Similarity:	229/409 - (55%)	Gaps:	19/409 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   481 QIPDW---LNIDDFKEIILSAEPNFEKILSSTSKLATKPGDNFASKLLKVEIEAQLKDNSVKTFS 542
            :||||   |:::.....:|........::.|...:..:.    .:.||.::::.||:|.::|...
  Fly     5 KIPDWVSSLSLNQAVHSVLEDGVQITSVIPSVHLIQFRN----CTVLLPIQVKVQLRDFTMKKLF 65

  Fly   543 YILKVH--SDNDAINFSDFNLFPKEIEVYSTYVPAFERFYKDVGLPVTFSPKSFRLSKDVSKEYL 605
            ::||..  :|..|:..:...:|.:|.:||...:|..|..|::||..|:|.|::|||...:..:|:
  Fly    66 FLLKAQHGTDIQAMVMNQLKMFQREHQVYHNVLPKLEEIYREVGKKVSFGPRAFRLDYSIGVQYV 130

  Fly   606 LLENLQPSGFKMVDRMIGMDLEHSKCTLKKLAQWHAASLKYKELNGPYSPKYNNGIFTEQTAPIF 670
            |||:|:...:|.|:|..|.:....|..||||||:||||....|.:|.:|....||::|:....:.
  Fly   131 LLEDLKAKSYKNVERQAGFNKLCLKQVLKKLAQFHAASAVCVEKHGAFSNLLVNGVYTKANESVL 195

  Fly   671 KGMFVNTKKSFIEEVSKFDGVDEYLHKMPEILDTYVDRILEDAKINEQAFNVLNHGDAWINNIMF 735
            :.:  |..:.|:.::.::...|.:..::.|.....||.:|:....:...||||||.|.|:||:||
  Fly   196 QEL--NDPEIFLSQLRRWRLGDHFHKRLVEKEKDLVDGLLKLHSPDSNEFNVLNHSDCWVNNVMF 258

  Fly   736 QYESDGRVKETLLLDHQVTKYGNPAQDLYYFIMSSTQLDIKVDQFDYLIRWYHQNMKEHAKLLNY 800
            :::..|.|::|.|||:|:.|||:||.||||.|:||.:.|||:.|||.::::|..::.::.|.||:
  Fly   259 KFDDSGHVEDTALLDYQLVKYGSPAIDLYYTILSSAEKDIKLAQFDNMVQYYFYHLLDNLKALNF 323

  Fly   801 NGFIPSLKELHAILIQHPIFAAGTVLTTLSM-CLNKTTDDFTTDSFLGNEENGKSLREAMFSNER 864
            .|.:|.|:.:...|.::.:.|...|...|.: .:|:..|:.       ||.....::.|||::.:
  Fly   324 GGSLPQLQHIRDALNKNGLAAYVVVTRALPITMMNQFEDEV-------NERYASKMKCAMFTSRK 381

  Fly   865 YRANIERVMPWINRRGLLD 883
            |...|:.::||:..|.||:
  Fly   382 YIQAIKDILPWMEERSLLN 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023	98/285 (34%)
CG31099	NP_733099.1	EcKinase	44..323	CDD:281023	98/280 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101022at50557
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850